CRCGN017_MCF10A.TP53.M_24H:M19 Gene Set
Genes
54 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:M19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
5.74675
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
5.20062
|
|
CLNS1A
|
chloride channel, nucleotide-sensitive, 1A
|
4.8846
|
|
GATA2
|
GATA binding protein 2
|
3.90848
|
|
ALG8
|
ALG8, alpha-1,3-glucosyltransferase
|
3.7568
|
|
RSF1
|
remodeling and spacing factor 1
|
3.0502
|
|
UVRAG
|
UV radiation resistance associated
|
2.98085
|
|
AAMDC
|
adipogenesis associated, Mth938 domain containing
|
2.8634
|
|
NARS2
|
asparaginyl-tRNA synthetase 2, mitochondrial (putative)
|
2.7312
|
|
THAP12
|
THAP domain containing 12
|
2.7055
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.67015
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.5665
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.55177
|
|
NDUFC2
|
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
|
2.48983
|
|
PKN1
|
protein kinase N1
|
2.39032
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
2.3574
|
|
SAMM50
|
SAMM50 sorting and assembly machinery component
|
2.34433
|
|
ASCC1
|
activating signal cointegrator 1 complex subunit 1
|
2.231
|
|
GAB2
|
GRB2-associated binding protein 2
|
2.2231
|
|
EMSY
|
EMSY transcriptional repressor, BRCA2 interacting
|
2.17295
|
|
OLFML2B
|
olfactomedin-like 2B
|
2.11515
|
|
HBB
|
hemoglobin, beta
|
2.06488
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
2.03605
|
|
FCHO1
|
FCH domain only 1
|
2.0178
|
|
ZNF217
|
zinc finger protein 217
|
2.0007
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
BLVRA
|
biliverdin reductase A
|
-4.7599
|
|
CDC20
|
cell division cycle 20
|
-4.7538
|
|
DNM1L
|
dynamin 1-like
|
-4.71435
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.80148
|
|
CAPRIN2
|
caprin family member 2
|
-3.45925
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.34805
|
|
YARS2
|
tyrosyl-tRNA synthetase 2, mitochondrial
|
-3.2742
|
|
SPAG7
|
sperm associated antigen 7
|
-2.80735
|
|
SINHCAF
|
SIN3-HDAC complex associated factor
|
-2.76145
|
|
MAPKAPK3
|
mitogen-activated protein kinase-activated protein kinase 3
|
-2.58748
|
|
SERPINA6
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
|
-2.321
|
|
ABITRAM
|
actin binding transcription modulator
|
-2.27025
|
|
TRAPPC8
|
trafficking protein particle complex 8
|
-2.26995
|
|
SNAI1
|
snail family zinc finger 1
|
-2.2368
|
|
LRRC40
|
leucine rich repeat containing 40
|
-2.23545
|
|
KIT
|
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
|
-2.22185
|
|
CD320
|
CD320 molecule
|
-2.1733
|
|
BBOF1
|
basal body orientation factor 1
|
-2.15555
|
|
WWC3
|
WWC family member 3
|
-2.15325
|
|
ERGIC2
|
ERGIC and golgi 2
|
-2.106
|
|
INTS13
|
integrator complex subunit 13
|
-2.0844
|
|
BAD
|
BCL2-associated agonist of cell death
|
-2.07923
|
|
KRT14
|
keratin 14, type I
|
-2.07745
|
|
CAPN2
|
calpain 2, (m/II) large subunit
|
-2.06715
|
|
PRDM8
|
PR domain containing 8
|
-2.0457
|
|
WTAP
|
Wilms tumor 1 associated protein
|
-2.04413
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.04175
|
|
NME7
|
NME/NM23 family member 7
|
-2.0216
|
|
TTC19
|
tetratricopeptide repeat domain 19
|
-2.0101
|
