CRCGN017_MCF10A.TP53.M_24H:M20 Gene Set
Genes
34 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:M20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAMLD1
|
mastermind-like domain containing 1
|
5.03619
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
4.8154
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
4.31447
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
3.41882
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
3.13719
|
|
AGR2
|
anterior gradient 2
|
3.11033
|
|
NRBF2
|
nuclear receptor binding factor 2
|
2.57032
|
|
GRB10
|
growth factor receptor-bound protein 10
|
2.33285
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.31532
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
2.26019
|
|
PDZK1
|
PDZ domain containing 1
|
2.25609
|
|
GSPT2
|
G1 to S phase transition 2
|
2.19196
|
|
TRAPPC13
|
trafficking protein particle complex 13
|
2.17791
|
|
SYNPO2L
|
synaptopodin 2-like
|
2.11821
|
|
CD37
|
CD37 molecule
|
2.09059
|
|
MTM1
|
myotubularin 1
|
2.08605
|
|
GFPT2
|
glutamine-fructose-6-phosphate transaminase 2
|
2.0211
|
|
CHN1
|
chimerin 1
|
2.00517
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.5312
|
|
GADD45B
|
growth arrest and DNA-damage-inducible, beta
|
-4.31634
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-4.31406
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-2.84911
|
|
UNC50
|
unc-50 homolog (C. elegans)
|
-2.51851
|
|
CNNM3
|
cyclin and CBS domain divalent metal cation transport mediator 3
|
-2.48989
|
|
GPBP1L1
|
GC-rich promoter binding protein 1-like 1
|
-2.44636
|
|
SRP9
|
signal recognition particle 9kDa
|
-2.38347
|
|
TMEM14B
|
transmembrane protein 14B
|
-2.28169
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
-2.26286
|
|
TMEM131
|
transmembrane protein 131
|
-2.23181
|
|
CXCL14
|
chemokine (C-X-C motif) ligand 14
|
-2.19049
|
|
COX5B
|
cytochrome c oxidase subunit Vb
|
-2.1552
|
|
PIH1D1
|
PIH1 domain containing 1
|
-2.11528
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
-2.10353
|
|
GBE1
|
glucan (1,4-alpha-), branching enzyme 1
|
-2.00201
|