CRCGN017_MCF10A.TP53.M_24H:M24 Gene Set

Dataset	Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category	transcriptomics
Type	small molecule perturbation
Description	(3s,16r,17s)-17-acetyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthrene-16-carbonitrile 11.48 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:M24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol	Name	Standardized Value
STAP2	signal transducing adaptor family member 2	4.52451
SSBP2	single-stranded DNA binding protein 2	3.68568
HDGFL3	HDGF like 3	3.40923
EGF	epidermal growth factor	3.16261
TXNRD1	thioredoxin reductase 1	2.36044
NOSIP	nitric oxide synthase interacting protein	2.30396
AMDHD2	amidohydrolase domain containing 2	2.24975
LIMD2	LIM domain containing 2	2.19844
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	2.06682
DHRS2	dehydrogenase/reductase (SDR family) member 2	2.05354

decreased expression

Symbol	Name	Standardized Value
SLC5A6	solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6	-3.88481
CD58	CD58 molecule	-3.70385
RPIA	ribose 5-phosphate isomerase A	-3.62853
CIAPIN1	cytokine induced apoptosis inhibitor 1	-2.76493
TOR1A	torsin family 1, member A (torsin A)	-2.7439
NGRN	neugrin, neurite outgrowth associated	-2.48114
KDM3A	lysine (K)-specific demethylase 3A	-2.33569
RPS5	ribosomal protein S5	-2.24868
TTC31	tetratricopeptide repeat domain 31	-2.22346