CRCGN017_MCF10A.TP53.M_24H:N08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ethylbenzene 33.43 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:N08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
USP6NL USP6 N-terminal like 6.30456
ADAM10 ADAM metallopeptidase domain 10 5.08588
KDM5D lysine (K)-specific demethylase 5D 4.68747
INTS3 integrator complex subunit 3 4.38493
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 3.28606
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 3.01869
HOXA10 homeobox A10 2.77418
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.7644
USP9Y ubiquitin specific peptidase 9, Y-linked 2.40615
DENND2D DENN/MADD domain containing 2D 2.34879
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 2.10197

decreased expression

Symbol Name Standardized Value
CCNB1 cyclin B1 -4.71008
HMG20B high mobility group 20B -4.25208
LYPLA1 lysophospholipase I -3.80293
THAP11 THAP domain containing 11 -3.13081
LOC124905557 eukaryotic translation initiation factor 1A, X-chromosomal -3.08809
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.61281
PUDP pseudouridine 5'-phosphatase -2.57421
OCEL1 occludin/ELL domain containing 1 -2.56851
GDF15 growth differentiation factor 15 -2.41364
SMC1A structural maintenance of chromosomes 1A -2.38649
KDM6A lysine (K)-specific demethylase 6A -2.29757
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 -2.28724
KDM5C lysine (K)-specific demethylase 5C -2.05598