| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | griseofulvin 33.52 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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122 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:N11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.9756 |
| H2BC12 | H2B clustered histone 12 | 4.15397 |
| TRIB1 | tribbles pseudokinase 1 | 3.78684 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 3.71949 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 3.71116 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 3.43696 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 3.24332 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 3.18452 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) | 2.95434 |
| RGS2 | regulator of G-protein signaling 2 | 2.95305 |
| H2BC9 | H2B clustered histone 9 | 2.86291 |
| RBM28 | RNA binding motif protein 28 | 2.67366 |
| ZNF180 | zinc finger protein 180 | 2.62598 |
| CCR2 | chemokine (C-C motif) receptor 2 | 2.54058 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.53159 |
| COMP | cartilage oligomeric matrix protein | 2.47319 |
| TMEM204 | transmembrane protein 204 | 2.43152 |
| H1-2 | H1.2 linker histone, cluster member | 2.37039 |
| RBM22 | RNA binding motif protein 22 | 2.35999 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.35844 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 2.35514 |
| DUSP5 | dual specificity phosphatase 5 | 2.33614 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | 2.31214 |
| TNIP1 | TNFAIP3 interacting protein 1 | 2.30251 |
| CERS2 | ceramide synthase 2 | 2.30092 |
| H2AC6 | H2A clustered histone 6 | 2.29287 |
| BIRC3 | baculoviral IAP repeat containing 3 | 2.28968 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 2.27962 |
| TPD52L2 | tumor protein D52-like 2 | 2.26188 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 2.24812 |
| LAP3 | leucine aminopeptidase 3 | 2.24382 |
| RHOG | ras homolog family member G | 2.24142 |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) | 2.24135 |
| TAF5 | TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa | 2.22307 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 2.19219 |
| RUBCN | rubicon autophagy regulator | 2.19202 |
| POLR1G | RNA polymerase I subunit G | 2.19075 |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 | 2.17002 |
| THAP1 | THAP domain containing, apoptosis associated protein 1 | 2.16782 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator | 2.1588 |
| RASIP1 | Ras interacting protein 1 | 2.14541 |
| GATA3 | GATA binding protein 3 | 2.14476 |
| AUNIP | aurora kinase A and ninein interacting protein | 2.13962 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 2.13101 |
| GALP | galanin-like peptide | 2.12652 |
| MIMS2 | mitochondrial inner membrane scaffold 2 | 2.11779 |
| TRAPPC4 | trafficking protein particle complex 4 | 2.10981 |
| H2BC4 | H2B clustered histone 4 | 2.09673 |
| MX1 | MX dynamin-like GTPase 1 | 2.08279 |
| RPAP3 | RNA polymerase II associated protein 3 | 2.06711 |
| GIMAP4 | GTPase, IMAP family member 4 | 2.06535 |
| MED17 | mediator complex subunit 17 | 2.0561 |
| GPATCH1 | G patch domain containing 1 | 2.04878 |
| VRK2 | vaccinia related kinase 2 | 2.03825 |
| SH2B3 | SH2B adaptor protein 3 | 2.03472 |
| ERCC6L | excision repair cross-complementation group 6-like | 2.03349 |
| HMOX1 | heme oxygenase 1 | 2.00687 |
| MTFR1 | mitochondrial fission regulator 1 | 2.0003 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | -5.78378 |
| NLRP4 | NLR family, pyrin domain containing 4 | -4.53776 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.12969 |
| GALE | UDP-galactose-4-epimerase | -4.0088 |
| CRTAP | cartilage associated protein | -3.98899 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -3.95389 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -3.5541 |
| CD58 | CD58 molecule | -3.43785 |
| CDK4 | cyclin-dependent kinase 4 | -3.29481 |
| TSPAN4 | tetraspanin 4 | -3.10908 |
| MRPS16 | mitochondrial ribosomal protein S16 | -3.03707 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -3.03061 |
| KRCC1 | lysine-rich coiled-coil 1 | -3.01069 |
| WASHC3 | WASH complex subunit 3 | -3.00389 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -2.91965 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | -2.83084 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | -2.82163 |
| COXFA4 | cytochrome c oxidase associated subunit FA4 | -2.80082 |
| CETN3 | centrin, EF-hand protein, 3 | -2.79569 |
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle | -2.78217 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -2.73517 |
| RPA3 | replication protein A3, 14kDa | -2.72659 |
| ATP5PF | ATP synthase peripheral stalk subunit F6 | -2.70781 |
| BLOC1S1 | biogenesis of lysosomal organelles complex-1, subunit 1 | -2.69335 |
| ATP5MF | ATP synthase membrane subunit f | -2.60341 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | -2.5933 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.57268 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) | -2.48744 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | -2.46023 |
| ATP5PD | ATP synthase peripheral stalk subunit d | -2.44443 |
| GNAS | GNAS complex locus | -2.44058 |
| NDUFB1 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | -2.43245 |
| PLTP | phospholipid transfer protein | -2.4243 |
| COG4 | component of oligomeric golgi complex 4 | -2.39864 |
| TRAPPC2L | trafficking protein particle complex 2-like | -2.38777 |
| FBXO34 | F-box protein 34 | -2.31418 |
| COX7B | cytochrome c oxidase subunit VIIb | -2.31317 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.31104 |
| CD81 | CD81 molecule | -2.29266 |
| DECR1 | 2,4-dienoyl CoA reductase 1, mitochondrial | -2.28017 |
| UQCR11 | ubiquinol-cytochrome c reductase, complex III subunit XI | -2.26778 |
| RPL10A | ribosomal protein L10a | -2.26748 |
| ATP5PO | ATP synthase peripheral stalk subunit OSCP | -2.26672 |
| ACBD4 | acyl-CoA binding domain containing 4 | -2.2654 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -2.25638 |
| HADH | hydroxyacyl-CoA dehydrogenase | -2.25074 |
| DNM1 | dynamin 1 | -2.2172 |
| COX5B | cytochrome c oxidase subunit Vb | -2.20116 |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | -2.19557 |
| TCTN1 | tectonic family member 1 | -2.1583 |
| ZMYM2 | zinc finger, MYM-type 2 | -2.14491 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.14339 |
| ACY1 | aminoacylase 1 | -2.14212 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | -2.14012 |
| GDF15 | growth differentiation factor 15 | -2.12927 |
| ACTR1B | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) | -2.11504 |
| ITM2B | integral membrane protein 2B | -2.09525 |
| HOXB3 | homeobox B3 | -2.06976 |
| TP53 | tumor protein p53 | -2.06801 |
| H3-3A | H3.3 histone A | -2.06224 |
| TSPAN31 | tetraspanin 31 | -2.05937 |
| PPA2 | pyrophosphatase (inorganic) 2 | -2.04483 |
| FKBP3 | FK506 binding protein 3, 25kDa | -2.03677 |
| RUSF1 | RUS family member 1 | -2.00986 |
