CRCGN017_MCF10A.TP53.M_24H:N13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description phenacetin 98.44 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

37 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:N13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RPL39L ribosomal protein L39-like 4.76877
CHMP6 charged multivesicular body protein 6 4.30464
VAV3 vav 3 guanine nucleotide exchange factor 4.2782
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.27591
ARID5B AT rich interactive domain 5B (MRF1-like) 3.5579
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 3.48269
AGR2 anterior gradient 2 3.41055
SRC SRC proto-oncogene, non-receptor tyrosine kinase 3.25995
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 3.05418
TIMP2 TIMP metallopeptidase inhibitor 2 2.94574
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.8404
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.71773
GSTZ1 glutathione S-transferase zeta 1 2.4725
MMP1 matrix metallopeptidase 1 2.43839
ARID4B AT rich interactive domain 4B (RBP1-like) 2.31439
ADAT1 adenosine deaminase, tRNA-specific 1 2.27928
PIH1D1 PIH1 domain containing 1 2.22041
TBX2 T-box 2 2.17438
SPIN2B spindlin family, member 2B 2.09012
NAT9 N-acetyltransferase 9 (GCN5-related, putative) 2.05067
PTPN20 protein tyrosine phosphatase, non-receptor type 20 2.03251
NUP153 nucleoporin 153kDa 2.00647

decreased expression

Symbol Name Standardized Value
GOLT1B golgi transport 1B -5.3845
RNF167 ring finger protein 167 -4.47147
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.47807
RECQL RecQ helicase-like -2.79012
TP53BP2 tumor protein p53 binding protein 2 -2.66608
ANKRD10 ankyrin repeat domain 10 -2.44855
CAB39 calcium binding protein 39 -2.39342
MTERF3 mitochondrial transcription termination factor 3 -2.29256
SPAG7 sperm associated antigen 7 -2.26756
SCRG1 stimulator of chondrogenesis 1 -2.2424
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -2.23014
GRN granulin -2.06639
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -2.06043
LYPLA1 lysophospholipase I -2.0109
STAT1 signal transducer and activator of transcription 1, 91kDa -2.00472