CRCGN017_MCF10A.TP53.M_24H:N14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description phenacetin 32.81 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

39 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:N14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MEF2C myocyte enhancer factor 2C 4.80879
CCNA1 cyclin A1 4.75441
MAMLD1 mastermind-like domain containing 1 4.735
PPARG peroxisome proliferator-activated receptor gamma 4.7197
SPAG4 sperm associated antigen 4 4.57807
ABHD4 abhydrolase domain containing 4 4.53801
TBX2 T-box 2 4.43489
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.2606
DOK5 docking protein 5 2.92187
PYCR1 pyrroline-5-carboxylate reductase 1 2.85261
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 2.783
MYF6 myogenic factor 6 (herculin) 2.61541
KHDC4 KH domain containing 4, pre-mRNA splicing factor 2.44854
ALAS1 5'-aminolevulinate synthase 1 2.42957
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 2.33314
MYOZ1 myozenin 1 2.31841
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 2.30421
MYOT myotilin 2.2454
PTPRR protein tyrosine phosphatase, receptor type, R 2.21553
MYL11 myosin light chain 11 2.17188
FZD4 frizzled class receptor 4 2.16484
MYBPH myosin binding protein H 2.14947
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 2.12885
TPM3 tropomyosin 3 2.09074
STARD8 StAR-related lipid transfer (START) domain containing 8 2.06552
SLN sarcolipin 2.06534
KCNK5 potassium channel, two pore domain subfamily K, member 5 2.05761
VIPR1 vasoactive intestinal peptide receptor 1 2.04099
FADD Fas (TNFRSF6)-associated via death domain 2.03943
TNNI1 troponin I type 1 (skeletal, slow) 2.02404

decreased expression

Symbol Name Standardized Value
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -8.25677
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.80562
HSPA1A heat shock 70kDa protein 1A -2.65057
OAT ornithine aminotransferase -2.63609
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.58409
CD7 CD7 molecule -2.29305
TSPAN5 tetraspanin 5 -2.25203
PLA2G15 phospholipase A2, group XV -2.18476
SQSTM1 sequestosome 1 -2.04668