CRCGN017_MCF10A.TP53.M_24H:N15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description phenacetin 10.94 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:N15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 3.17133
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.21275
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.12571
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.0806

decreased expression

Symbol Name Standardized Value
NUP85 nucleoporin 85kDa -4.53768
KCTD2 potassium channel tetramerization domain containing 2 -2.71128
MRPL58 mitochondrial ribosomal protein L58 -2.66275
LLGL2 lethal giant larvae homolog 2 (Drosophila) -2.4688
MRPS7 mitochondrial ribosomal protein S7 -2.46389
NT5C 5', 3'-nucleotidase, cytosolic -2.34642
GDF15 growth differentiation factor 15 -2.34393
TUBA4A tubulin, alpha 4a -2.31736
SUMO4 small ubiquitin-like modifier 4 -2.26546
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -2.12389
WBP2 WW domain binding protein 2 -2.0889
TMEM94 transmembrane protein 94 -2.07321
HMG20B high mobility group 20B -2.03756