CRCGN017_MCF10A.TP53.M_24H:N19 Gene Set
Dataset
Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category
transcriptomics
Type
small molecule perturbation
Description
trisodium 5-oxo-1-(4-sulfonatophenyl)-4-[(e)-(4-sulfonatophenyl)diazenyl]-2,5-dihydro-1h-pyrazole-3-carboxylate 100.87 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome )
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Genes
18 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:N19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
Symbol
Name
Standardized Value
ABHD6
abhydrolase domain containing 6
4.58689
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
4.46142
ADAM10
ADAM metallopeptidase domain 10
4.29382
PPARG
peroxisome proliferator-activated receptor gamma
3.87561
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
2.85574
ACAA1
acetyl-CoA acyltransferase 1
2.59463
NUP133
nucleoporin 133kDa
2.38936
SPDEF
SAM pointed domain containing ETS transcription factor
2.28658
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
2.28057
HBA1
hemoglobin, alpha 1
2.26192
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
2.21456
RIC8A
RIC8 guanine nucleotide exchange factor A
2.1123
DHRS2
dehydrogenase/reductase (SDR family) member 2
2.01985
decreased expression
Symbol
Name
Standardized Value
SCYL3
SCY1-like 3 (S. cerevisiae)
-4.76417
KRT14
keratin 14, type I
-4.18093
OXA1L
oxidase (cytochrome c) assembly 1-like
-2.86332
DCK
deoxycytidine kinase
-2.39394
MLEC
malectin
-2.37148
