CRCGN017_MCF10A.TP53.M_24H:N21 Gene Set
Dataset
Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category
transcriptomics
Type
small molecule perturbation
Description
trisodium 5-oxo-1-(4-sulfonatophenyl)-4-[(e)-(4-sulfonatophenyl)diazenyl]-2,5-dihydro-1h-pyrazole-3-carboxylate 11.21 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome )
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Genes
22 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:N21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
Symbol
Name
Standardized Value
CCL2
chemokine (C-C motif) ligand 2
5.15996
TSEN2
TSEN2 tRNA splicing endonuclease subunit
4.41711
SPAG4
sperm associated antigen 4
4.06795
DYRK3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
3.982
DCUN1D4
DCN1, defective in cullin neddylation 1, domain containing 4
3.91417
AMDHD2
amidohydrolase domain containing 2
3.88786
KLHL9
kelch-like family member 9
3.58775
SGCB
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
3.18546
USP6NL
USP6 N-terminal like
2.56671
GNA15
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
2.43234
DFFA
DNA fragmentation factor, 45kDa, alpha polypeptide
2.3096
CD53
CD53 molecule
2.25707
VPS28
vacuolar protein sorting 28 homolog (S. cerevisiae)
2.2109
SLC25A13
solute carrier family 25 (aspartate/glutamate carrier), member 13
2.12346
decreased expression
Symbol
Name
Standardized Value
ADI1
acireductone dioxygenase 1
-4.58723
CYCS
cytochrome c, somatic
-4.25561
CCNB1
cyclin B1
-4.09162
PCCB
propionyl CoA carboxylase, beta polypeptide
-3.35601
NT5DC2
5'-nucleotidase domain containing 2
-2.79618
THAP11
THAP domain containing 11
-2.77995
LOC127933115
uncharacterized LOC127933115
-2.14621
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
-2.03941
