CRCGN017_MCF10A.TP53.M_24H:N22 Gene Set
Genes
30 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:N22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
WFS1
|
Wolfram syndrome 1 (wolframin)
|
4.34499
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.1575
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
4.02719
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.73433
|
|
SPAG4
|
sperm associated antigen 4
|
3.58437
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
3.44097
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
3.24145
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
2.84831
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
2.46351
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.38607
|
|
KDM5D
|
lysine (K)-specific demethylase 5D
|
2.19429
|
|
EEF1A2
|
eukaryotic translation elongation factor 1 alpha 2
|
2.07783
|
|
IL1B
|
interleukin 1, beta
|
2.03083
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MPC2
|
mitochondrial pyruvate carrier 2
|
-5.04826
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.92765
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-4.30666
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.12631
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.87742
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.133
|
|
BLCAP
|
bladder cancer associated protein
|
-2.77118
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
-2.58703
|
|
POLE3
|
polymerase (DNA directed), epsilon 3, accessory subunit
|
-2.50924
|
|
COTL1
|
coactosin-like F-actin binding protein 1
|
-2.46435
|
|
SMC1A
|
structural maintenance of chromosomes 1A
|
-2.44854
|
|
BSPRY
|
B-box and SPRY domain containing
|
-2.44436
|
|
TOR1A
|
torsin family 1, member A (torsin A)
|
-2.24046
|
|
CORO1A
|
coronin, actin binding protein, 1A
|
-2.15256
|
|
PADI1
|
peptidyl arginine deiminase, type I
|
-2.03854
|
|
PSRC1
|
proline/serine-rich coiled-coil 1
|
-2.02196
|
|
HDHD3
|
haloacid dehalogenase-like hydrolase domain containing 3
|
-2.0198
|
