CRCGN017_MCF10A.TP53.M_24H:O04 Gene Set
Genes
38 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:O04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
5.49126
|
|
STK10
|
serine/threonine kinase 10
|
5.15481
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
5.12415
|
|
SPAG4
|
sperm associated antigen 4
|
4.5045
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
4.45371
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
4.11768
|
|
AGR2
|
anterior gradient 2
|
3.74375
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
3.19523
|
|
FZD7
|
frizzled class receptor 7
|
2.75269
|
|
CTCF
|
CCCTC-binding factor (zinc finger protein)
|
2.70267
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.58162
|
|
FUBP3
|
far upstream element (FUSE) binding protein 3
|
2.51309
|
|
NRBF2
|
nuclear receptor binding factor 2
|
2.4911
|
|
SERF1A
|
small EDRK-rich factor 1A (telomeric)
|
2.28627
|
|
HNRNPAB
|
heterogeneous nuclear ribonucleoprotein A/B
|
2.28537
|
|
RBM22
|
RNA binding motif protein 22
|
2.23538
|
|
NUDT19
|
nudix (nucleoside diphosphate linked moiety X)-type motif 19
|
2.23362
|
|
ZBTB35
|
zinc finger and BTB domain containing 35
|
2.22289
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
2.14817
|
|
CBLL1
|
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
|
2.14526
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HMG20B
|
high mobility group 20B
|
-4.43877
|
|
HAT1
|
histone acetyltransferase 1
|
-4.2572
|
|
PMM2
|
phosphomannomutase 2
|
-4.19454
|
|
KIF20A
|
kinesin family member 20A
|
-3.82165
|
|
NUP85
|
nucleoporin 85kDa
|
-3.76788
|
|
GDF15
|
growth differentiation factor 15
|
-3.55879
|
|
TUBA4A
|
tubulin, alpha 4a
|
-3.46432
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.39114
|
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast)
|
-3.37567
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.06353
|
|
GRN
|
granulin
|
-2.93536
|
|
MRPL58
|
mitochondrial ribosomal protein L58
|
-2.73529
|
|
PRUNE2
|
prune homolog 2 (Drosophila)
|
-2.55255
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.55227
|
|
TMEM94
|
transmembrane protein 94
|
-2.30332
|
|
STXBP2
|
syntaxin binding protein 2
|
-2.07298
|
|
NAT9
|
N-acetyltransferase 9 (GCN5-related, putative)
|
-2.05606
|
|
SCN3A
|
sodium channel, voltage gated, type III alpha subunit
|
-2.01303
|