CRCGN017_MCF10A.TP53.M_24H:O05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description UnTrt perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:O05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FKBP14 FK506 binding protein 14, 22 kDa 4.57093
CXCR4 chemokine (C-X-C motif) receptor 4 4.54057
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.17964
CCDC85B coiled-coil domain containing 85B 3.13098
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.92328
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.88252
HBA1 hemoglobin, alpha 1 2.80454
NOSIP nitric oxide synthase interacting protein 2.67222
LY86 lymphocyte antigen 86 2.22261
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.17389
TOMM34 translocase of outer mitochondrial membrane 34 2.17175

decreased expression

Symbol Name Standardized Value
TM9SF2 transmembrane 9 superfamily member 2 -3.8062
CANT1 calcium activated nucleotidase 1 -3.47428
ATF5 activating transcription factor 5 -3.38355
CREB1 cAMP responsive element binding protein 1 -2.82557
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.60619
ATP11B ATPase, class VI, type 11B -2.19251
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -2.16695
RAI14 retinoic acid induced 14 -2.11877