CRCGN017_MCF10A.TP53.M_24H:O06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description UnTrt perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

27 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:O06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 3.33926
CCNF cyclin F 3.16346
RPL39L ribosomal protein L39-like 3.014
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.90113
PYGO1 pygopus family PHD finger 1 2.38152
DDN dendrin 2.22244
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.17547
SCN5A sodium channel, voltage gated, type V alpha subunit 2.17119
HPCA hippocalcin 2.12694
ARL2BP ADP-ribosylation factor-like 2 binding protein 2.04426
GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 2.04416
COL3A1 collagen, type III, alpha 1 2.02537
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 2.01872
CSRNP3 cysteine-serine-rich nuclear protein 3 2.00727

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -9.58411
UFM1 ubiquitin-fold modifier 1 -5.03243
PCCB propionyl CoA carboxylase, beta polypeptide -4.37547
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -4.33168
HSPA1A heat shock 70kDa protein 1A -3.95995
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.81599
R3HDM4 R3H domain containing 4 -2.2659
MFSD12 major facilitator superfamily domain containing 12 -2.15825
PABPC3 poly(A) binding protein, cytoplasmic 3 -2.12274
MSN moesin -2.10297
VAT1 vesicle amine transport 1 -2.07574
RNF220 ring finger protein 220 -2.01377
COTL1 coactosin-like F-actin binding protein 1 -2.01269