| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | cytembena 11.15 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
91 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:O09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMOX1 | heme oxygenase 1 | 10.0 |
| TXNRD1 | thioredoxin reductase 1 | 6.97737 |
| ALAS1 | 5'-aminolevulinate synthase 1 | 4.57914 |
| UGDH | UDP-glucose 6-dehydrogenase | 4.36051 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 3.54889 |
| CADM1 | cell adhesion molecule 1 | 3.45866 |
| GLRX | glutaredoxin (thioltransferase) | 3.45101 |
| OXSR1 | oxidative stress responsive 1 | 3.39825 |
| CORO1A | coronin, actin binding protein, 1A | 3.38884 |
| PRKX | protein kinase, X-linked | 3.34515 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 3.33636 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 3.32566 |
| TBX2 | T-box 2 | 3.20272 |
| SQSTM1 | sequestosome 1 | 3.11899 |
| TRIM16 | tripartite motif containing 16 | 2.9756 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 2.92752 |
| KLHL9 | kelch-like family member 9 | 2.87805 |
| LAP3 | leucine aminopeptidase 3 | 2.85117 |
| GPC1 | glypican 1 | 2.80094 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 2.69591 |
| KLHL21 | kelch-like family member 21 | 2.68868 |
| HBB | hemoglobin, beta | 2.64346 |
| CDK19 | cyclin-dependent kinase 19 | 2.58178 |
| HBA1 | hemoglobin, alpha 1 | 2.55974 |
| TSKU | tsukushi, small leucine rich proteoglycan | 2.47108 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 | 2.4675 |
| GATA2 | GATA binding protein 2 | 2.45041 |
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 | 2.34442 |
| RNF44 | ring finger protein 44 | 2.27185 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 2.27019 |
| ABHD4 | abhydrolase domain containing 4 | 2.26326 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 2.25058 |
| PVRIG | poliovirus receptor related immunoglobulin domain containing | 2.17484 |
| AVPI1 | arginine vasopressin-induced 1 | 2.14679 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 | 2.14108 |
| NR1I3 | nuclear receptor subfamily 1, group I, member 3 | 2.12378 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 2.12311 |
| RBBP5 | retinoblastoma binding protein 5 | 2.11655 |
| PPP6R1 | protein phosphatase 6, regulatory subunit 1 | 2.07606 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 2.07573 |
| RAB25 | RAB25, member RAS oncogene family | 2.07089 |
| PIR | pirin (iron-binding nuclear protein) | 2.07082 |
| KYNU | kynureninase | 2.0519 |
| RAB21 | RAB21, member RAS oncogene family | 2.04203 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 2.04019 |
| UNKL | unkempt family zinc finger-like | 2.03424 |
| FLRT1 | fibronectin leucine rich transmembrane protein 1 | 2.03368 |
| EEIG1 | estrogen-induced osteoclastogenesis regulator 1 | 2.02914 |
| RGS16 | regulator of G-protein signaling 16 | 2.02396 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HOXA5 | homeobox A5 | -6.43521 |
| DSG2 | desmoglein 2 | -4.44086 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial | -3.88935 |
| PCNA | proliferating cell nuclear antigen | -3.88452 |
| DNM1L | dynamin 1-like | -3.85937 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.65028 |
| MSN | moesin | -3.58324 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -3.26989 |
| GOLT1B | golgi transport 1B | -3.16311 |
| MED21 | mediator complex subunit 21 | -3.16011 |
| HMG20B | high mobility group 20B | -3.13211 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.11693 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.96711 |
| KRT14 | keratin 14, type I | -2.87473 |
| RECQL | RecQ helicase-like | -2.8451 |
| TRAPPC3 | trafficking protein particle complex 3 | -2.74928 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.7399 |
| CAPRIN2 | caprin family member 2 | -2.66969 |
| VAT1 | vesicle amine transport 1 | -2.66562 |
| FHL2 | four and a half LIM domains 2 | -2.54178 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.53992 |
| STK25 | serine/threonine kinase 25 | -2.50982 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -2.41035 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -2.37852 |
| INTS3 | integrator complex subunit 3 | -2.37606 |
| INTS13 | integrator complex subunit 13 | -2.31916 |
| ATP13A2 | ATPase type 13A2 | -2.28664 |
| VPS35 | vacuolar protein sorting 35 homolog (S. cerevisiae) | -2.27078 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | -2.21628 |
| HOXA4 | homeobox A4 | -2.19458 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -2.19457 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -2.1648 |
| LDHB | lactate dehydrogenase B | -2.11185 |
| MSMO1 | methylsterol monooxygenase 1 | -2.09487 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.0548 |
| YBX3 | Y box binding protein 3 | -2.05037 |
| CETN2 | centrin, EF-hand protein, 2 | -2.04773 |
| ANKRD10 | ankyrin repeat domain 10 | -2.04595 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -2.03558 |
| HOXA7 | homeobox A7 | -2.02753 |
| LRRC59 | leucine rich repeat containing 59 | -2.02581 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -2.02209 |
