CRCGN017_MCF10A.TP53.M_24H:O11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 5-methylchrysene 32.63 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

435 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:O11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MMP2 matrix metallopeptidase 2 3.6107
RBP4 retinol binding protein 4, plasma 3.59977
CXCR4 chemokine (C-X-C motif) receptor 4 3.44902
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 3.31915
TENT4A terminal nucleotidyltransferase 4A 3.27836
LAP3 leucine aminopeptidase 3 3.24807
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 3.24205
TGFB3 transforming growth factor, beta 3 3.18769
CA7 carbonic anhydrase VII 3.10717
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 3.08047
TESK1 testis-specific kinase 1 3.0259
FCHO1 FCH domain only 1 3.01644
FZD1 frizzled class receptor 1 3.00922
ESM1 endothelial cell-specific molecule 1 2.94403
MYL9 myosin, light chain 9, regulatory 2.92114
AURKB aurora kinase B 2.92062
TEDC2 tubulin epsilon and delta complex 2 2.91343
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 2.90708
GADD45A growth arrest and DNA-damage-inducible, alpha 2.90677
TREML2 triggering receptor expressed on myeloid cells-like 2 2.90092
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.87088
TIMP2 TIMP metallopeptidase inhibitor 2 2.86063
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 2.8293
CERK ceramide kinase 2.82348
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 2.79788
PPOX protoporphyrinogen oxidase 2.78153
HYOU1 hypoxia up-regulated 1 2.77426
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.76761
PLCL1 phospholipase C-like 1 2.76294
A1CF APOBEC1 complementation factor 2.75971
SOCS2 suppressor of cytokine signaling 2 2.75795
LATS1 large tumor suppressor kinase 1 2.75192
H2BC21 H2B clustered histone 21 2.74231
GRB7 growth factor receptor-bound protein 7 2.72688
CD1B CD1b molecule 2.66947
LOC102725023 killer cell immunoglobulin-like receptor 2DS3 allele 0020101 2.66724
ACVRL1 activin A receptor type II-like 1 2.65499
MMP10 matrix metallopeptidase 10 2.64521
LRRK1 leucine-rich repeat kinase 1 2.64359
ZNF154 zinc finger protein 154 2.63113
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 2.62622
KLHL21 kelch-like family member 21 2.62123
ANGPTL8 angiopoietin like 8 2.61789
MC4R melanocortin 4 receptor 2.61382
ZNF682 zinc finger protein 682 2.58363
PRTN3 proteinase 3 2.57752
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 2.57324
ZNF318 zinc finger protein 318 2.55636
MOB3B MOB kinase activator 3B 2.55628
PRDM14 PR domain containing 14 2.5557
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 2.55513
CIAO3 cytosolic iron-sulfur assembly component 3 2.54836
MTOR mechanistic target of rapamycin (serine/threonine kinase) 2.54429
COMP cartilage oligomeric matrix protein 2.54397
IFNAR1 interferon (alpha, beta and omega) receptor 1 2.5412
OR2C1 olfactory receptor, family 2, subfamily C, member 1 2.53714
ZNF550 zinc finger protein 550 2.53705
FSD1 fibronectin type III and SPRY domain containing 1 2.5259
CD200 CD200 molecule 2.52107
CYRIA CYFIP related Rac1 interactor A 2.51264
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.50111
APOB apolipoprotein B 2.49929
RASL10A RAS-like, family 10, member A 2.49333
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.47128
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 2.47115
MACO1 macoilin 1 2.46681
CCR9 chemokine (C-C motif) receptor 9 2.46536
FANCG Fanconi anemia, complementation group G 2.46377
TMEM39B transmembrane protein 39B 2.46332
GRPR gastrin-releasing peptide receptor 2.46117
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.45965
DOT1L DOT1-like histone H3K79 methyltransferase 2.4564
MRPL37 mitochondrial ribosomal protein L37 2.45521
VEGFA vascular endothelial growth factor A 2.45154
C8G complement component 8, gamma polypeptide 2.44276
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 2.43966
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 2.43799
THRB thyroid hormone receptor, beta 2.43204
NIT1 nitrilase 1 2.42717
ZNF273 zinc finger protein 273 2.42578
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 2.42507
GDAP1 ganglioside induced differentiation associated protein 1 2.42322
SOX2 SRY (sex determining region Y)-box 2 2.41641
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 2.41512
MMP1 matrix metallopeptidase 1 2.40458
KMT2D lysine (K)-specific methyltransferase 2D 2.39025
SLC35E2B solute carrier family 35, member E2B 2.38661
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 2.3863
MMP13 matrix metallopeptidase 13 2.37991
DNAH2 dynein, axonemal, heavy chain 2 2.37837
SCN2A sodium channel, voltage gated, type II alpha subunit 2.36029
OR10J1 olfactory receptor, family 10, subfamily J, member 1 2.35952
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.34891
MEIS2 Meis homeobox 2 2.34712
HROB homologous recombination factor with OB-fold 2.34133
TMEM143 transmembrane protein 143 2.33889
ZNF34 zinc finger protein 34 2.33783
GCGR glucagon receptor 2.3335
NTF3 neurotrophin 3 2.3312
SPRED2 sprouty-related, EVH1 domain containing 2 2.32694
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa 2.32257
ELANE elastase, neutrophil expressed 2.31805
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.31525
RECK reversion-inducing-cysteine-rich protein with kazal motifs 2.31503
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 2.31007
HHLA1 HERV-H LTR-associating 1 2.30944
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 2.30249
RNF115 ring finger protein 115 2.30108
EGF epidermal growth factor 2.29949
POLR1E polymerase (RNA) I polypeptide E, 53kDa 2.29803
TRHR thyrotropin-releasing hormone receptor 2.29528
CETN3 centrin, EF-hand protein, 3 2.29359
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.29153
DUSP21 dual specificity phosphatase 21 2.29115
RFX3 regulatory factor X, 3 (influences HLA class II expression) 2.28925
VENTX VENT homeobox 2.28864
FGF23 fibroblast growth factor 23 2.28682
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 2.28594
TAC3 tachykinin 3 2.28256
DOC2B double C2-like domains, beta 2.28124
ZNF804A zinc finger protein 804A 2.27999
RNF31 ring finger protein 31 2.27888
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 2.27816
SRY sex determining region Y 2.27801
EGLN3 egl-9 family hypoxia-inducible factor 3 2.27434
SNAI2 snail family zinc finger 2 2.2737
RFTN1 raftlin, lipid raft linker 1 2.27245
TP73 tumor protein p73 2.26987
KLF3 Kruppel-like factor 3 (basic) 2.26818
CEP170B centrosomal protein 170B 2.26732
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa 2.26617
SNAP29 synaptosomal-associated protein, 29kDa 2.2656
LOC102724652 alpha-crystallin A chain 2.26184
DGCR2 DiGeorge syndrome critical region gene 2 2.26074
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 2.25757
RGS16 regulator of G-protein signaling 16 2.25087
VAC14 Vac14 homolog (S. cerevisiae) 2.24864
WASHC5 WASH complex subunit 5 2.24478
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 2.24327
RAG1 recombination activating gene 1 2.24262
TAS2R3 taste receptor, type 2, member 3 2.24016
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 2.23982
NOTCH4 notch 4 2.23981
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 2.23386
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.23291
PDE2A phosphodiesterase 2A, cGMP-stimulated 2.23283
PYY peptide YY 2.23137
GALR3 galanin receptor 3 2.22954
EAPP E2F-associated phosphoprotein 2.22563
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 2.22511
CLDN14 claudin 14 2.22371
ARHGAP25 Rho GTPase activating protein 25 2.22263
NLGN4Y neuroligin 4, Y-linked 2.22158
DIPK1A divergent protein kinase domain 1A 2.21893
DRP2 dystrophin related protein 2 2.21754
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 2.21719
KATNIP katanin interacting protein 2.21092
TRIM10 tripartite motif containing 10 2.20575
DOK5 docking protein 5 2.20187
ICAM5 intercellular adhesion molecule 5, telencephalin 2.20164
KDM8 lysine (K)-specific demethylase 8 2.1996
PRMT7 protein arginine methyltransferase 7 2.19867
SLC26A4 solute carrier family 26 (anion exchanger), member 4 2.19713
BCL2L11 BCL2-like 11 (apoptosis facilitator) 2.19624
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 2.1942
GALT galactose-1-phosphate uridylyltransferase 2.19131
SSTR4 somatostatin receptor 4 2.19091
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4 2.1908
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 2.18927
ADRA2B adrenoceptor alpha 2B 2.18848
APOH apolipoprotein H (beta-2-glycoprotein I) 2.18836
CLCNKB chloride channel, voltage-sensitive Kb 2.18431
KLF13 Kruppel-like factor 13 2.18412
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.18352
FGFR2 fibroblast growth factor receptor 2 2.1833
KCNK5 potassium channel, two pore domain subfamily K, member 5 2.18053
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 2.17966
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) 2.179
MTAP methylthioadenosine phosphorylase 2.17889
ADTRP androgen-dependent TFPI-regulating protein 2.17644
CNTFR ciliary neurotrophic factor receptor 2.17547
OPN1MW3 opsin 1, medium wave sensitive 3 2.17449
SCN3B sodium channel, voltage gated, type III beta subunit 2.17385
CD40 CD40 molecule, TNF receptor superfamily member 5 2.17374
WDR7 WD repeat domain 7 2.17265
DNASE1 deoxyribonuclease I 2.17254
NTNG2 netrin G2 2.17155
CCDC177 coiled-coil domain containing 177 2.17107
ANGPTL2 angiopoietin-like 2 2.17042
PRKX protein kinase, X-linked 2.16935
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.16923
CAMKV CaM kinase-like vesicle-associated 2.16664
LRRC3 leucine rich repeat containing 3 2.16588
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 2.16446
DEFA4 defensin, alpha 4, corticostatin 2.16219
INTS11 integrator complex subunit 11 2.15993
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 2.15661
CD1E CD1e molecule 2.15174
HLA-DMA major histocompatibility complex, class II, DM alpha 2.15162
GUCA2B guanylate cyclase activator 2B (uroguanylin) 2.15111
SYN1 synapsin I 2.15098
APOC3 apolipoprotein C-III 2.14972
MOCS1 molybdenum cofactor synthesis 1 2.1478
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 2.14731
NHERF4 NHERF family PDZ scaffold protein 4 2.14412
DAO D-amino-acid oxidase 2.14411
FRMD1 FERM domain containing 1 2.14215
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 2.1415
KIF26B kinesin family member 26B 2.14148
DPYS dihydropyrimidinase 2.1405
TM4SF5 transmembrane 4 L six family member 5 2.13938
COL8A2 collagen, type VIII, alpha 2 2.13733
RGL2 ral guanine nucleotide dissociation stimulator-like 2 2.13715
NECAB2 N-terminal EF-hand calcium binding protein 2 2.13507
ADAM11 ADAM metallopeptidase domain 11 2.13324
GHSR growth hormone secretagogue receptor 2.1319
OR1E1 olfactory receptor, family 1, subfamily E, member 1 2.13044
AANAT aralkylamine N-acetyltransferase 2.12989
RASA2 RAS p21 protein activator 2 2.1293
KERA keratocan 2.12786
CLXN calaxin 2.12665
SSTR2 somatostatin receptor 2 2.12624
MED9 mediator complex subunit 9 2.12514
MMP9 matrix metallopeptidase 9 2.12225
RGCC regulator of cell cycle 2.12194
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.11959
TRAPPC6A trafficking protein particle complex 6A 2.11735
PRDM5 PR domain containing 5 2.11725
GJA9 gap junction protein, alpha 9, 59kDa 2.11647
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 2.11458
ZNF250 zinc finger protein 250 2.11384
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 2.1124
EHMT2 euchromatic histone-lysine N-methyltransferase 2 2.11164
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.1109
ADGRG3 adhesion G protein-coupled receptor G3 2.10982
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa 2.10945
OR3A3 olfactory receptor, family 3, subfamily A, member 3 2.10876
ARMCX4 armadillo repeat containing, X-linked 4 2.10814
PCDHGA9 protocadherin gamma subfamily A, 9 2.1081
CES2 carboxylesterase 2 2.10649
PCDHGA8 protocadherin gamma subfamily A, 8 2.10591
ACTL8 actin-like 8 2.10514
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma 2.1047
PLVAP plasmalemma vesicle associated protein 2.10453
PGLYRP1 peptidoglycan recognition protein 1 2.10239
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 2.09937
G6PC1 glucose-6-phosphatase catalytic subunit 1 2.09838
GDF9 growth differentiation factor 9 2.09802
GRIK4 glutamate receptor, ionotropic, kainate 4 2.09741
MTSS2 MTSS I-BAR domain containing 2 2.09734
ZNF696 zinc finger protein 696 2.09688
INSRR insulin receptor-related receptor 2.09379
RRH retinal pigment epithelium-derived rhodopsin homolog 2.09365
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 2.09362
ZNG1A Zn regulated GTPase metalloprotein activator 1A 2.09322
SAMD4B sterile alpha motif domain containing 4B 2.08803
FOXE3 forkhead box E3 2.08785
TJAP1 tight junction associated protein 1 (peripheral) 2.0876
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 2.08737
MTNR1A melatonin receptor 1A 2.08431
ZNF132 zinc finger protein 132 2.08373
SMG9 SMG9 nonsense mediated mRNA decay factor 2.08334
PKDREJ polycystin (PKD) family receptor for egg jelly 2.08321
ZNF701 zinc finger protein 701 2.08188
CXCL11 chemokine (C-X-C motif) ligand 11 2.08023
CDIP1 cell death-inducing p53 target 1 2.0796
PCDHA9 protocadherin alpha 9 2.07935
IGFBP3 insulin-like growth factor binding protein 3 2.07924
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 2.07893
ASMT acetylserotonin O-methyltransferase 2.0778
BMP4 bone morphogenetic protein 4 2.07505
RNF44 ring finger protein 44 2.07267
TSHZ2 teashirt zinc finger homeobox 2 2.07107
TAS2R13 taste receptor, type 2, member 13 2.07038
GCG glucagon 2.0693
SLC75A1 solute carrier family 75 member 1 2.06897
PLA2G2E phospholipase A2, group IIE 2.06861
CFHR2 complement factor H-related 2 2.06808
IL12RB1 interleukin 12 receptor, beta 1 2.06716
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.06596
ADGRL4 adhesion G protein-coupled receptor L4 2.06529
LY6H lymphocyte antigen 6 complex, locus H 2.06481
OR3A1 olfactory receptor, family 3, subfamily A, member 1 2.06436
CLDN6 claudin 6 2.06381
TMEM8B transmembrane protein 8B 2.06374
PAX5 paired box 5 2.0623
SLC7A4 solute carrier family 7, member 4 2.06164
ASGR2 asialoglycoprotein receptor 2 2.05781
FGF5 fibroblast growth factor 5 2.05761
TBC1D31 TBC1 domain family, member 31 2.05717
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 2.05456
ANO2 anoctamin 2, calcium activated chloride channel 2.05428
PDCD1LG2 programmed cell death 1 ligand 2 2.05411
OVOL3 ovo-like zinc finger 3 2.05364
MMP24 matrix metallopeptidase 24 (membrane-inserted) 2.05282
HINFP histone H4 transcription factor 2.05143
PKLR pyruvate kinase, liver and RBC 2.05121
PRAMEF10 PRAME family member 10 2.05058
HSPA6 heat shock 70kDa protein 6 (HSP70B') 2.04959
ONECUT1 one cut homeobox 1 2.04937
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 2.0488
NT5E 5'-nucleotidase, ecto (CD73) 2.04802
FAM135A family with sequence similarity 135, member A 2.04667
FRMPD4 FERM and PDZ domain containing 4 2.04588
PRR14L proline rich 14-like 2.04547
HOXD9 homeobox D9 2.04543
SSBP3 single stranded DNA binding protein 3 2.04474
ZNF559-ZNF177 ZNF559-ZNF177 readthrough 2.0441
WDR46 WD repeat domain 46 2.04357
GPRC5D G protein-coupled receptor, class C, group 5, member D 2.04288
NPVF neuropeptide VF precursor 2.04096
ZNF232 zinc finger protein 232 2.04089
MED22 mediator complex subunit 22 2.03767
RAB43 RAB43, member RAS oncogene family 2.03766
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 2.03761
TERT telomerase reverse transcriptase 2.03761
HSF1 heat shock transcription factor 1 2.03678
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 2.03559
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa 2.035
PEX6 peroxisomal biogenesis factor 6 2.0349
THPO thrombopoietin 2.03486
COL6A1 collagen, type VI, alpha 1 2.03418
SHB Src homology 2 domain containing adaptor protein B 2.03334
LINC02854 long intergenic non-protein coding RNA 2854 2.03319
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 2.03289
FLT1 fms-related tyrosine kinase 1 2.03278
FOXH1 forkhead box H1 2.03073
PON3 paraoxonase 3 2.02939
VTN vitronectin 2.02708
DCHS1 dachsous cadherin-related 1 2.02706
ORM2 orosomucoid 2 2.02619
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 2.02611
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) 2.02593
SNX13 sorting nexin 13 2.0259
ADGRB2 adhesion G protein-coupled receptor B2 2.02519
GPR173 G protein-coupled receptor 173 2.02512
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 2.02492
ZNF85 zinc finger protein 85 2.02435
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.02418
ZNF500 zinc finger protein 500 2.02414
NOX4 NADPH oxidase 4 2.02377
SEMG1 semenogelin I 2.02335
PHF13 PHD finger protein 13 2.02278
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 2.02262
CNPY3 canopy FGF signaling regulator 3 2.02257
VILL villin-like 2.02176
INSL5 insulin-like 5 2.02123
CUZD1 CUB and zona pellucida-like domains 1 2.021
AJAP1 adherens junctions associated protein 1 2.01989
ASGR1 asialoglycoprotein receptor 1 2.01862
EMILIN2 elastin microfibril interfacer 2 2.01823
PEX26 peroxisomal biogenesis factor 26 2.01768
MAST3 microtubule associated serine/threonine kinase 3 2.0176
PHKG2 phosphorylase kinase, gamma 2 (testis) 2.01685
GDF3 growth differentiation factor 3 2.01641
RCVRN recoverin 2.0163
CD1C CD1c molecule 2.01469
PRKCE protein kinase C, epsilon 2.01395
ERN1 endoplasmic reticulum to nucleus signaling 1 2.01345
CDK11A cyclin-dependent kinase 11A 2.01144
TRPC7 transient receptor potential cation channel, subfamily C, member 7 2.01031
KNG1 kininogen 1 2.00997
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 2.00903
ORM1 orosomucoid 1 2.00831
BEND5 BEN domain containing 5 2.00582
CLDN17 claudin 17 2.0056
FAM76A family with sequence similarity 76, member A 2.00536
GRK5 G protein-coupled receptor kinase 5 2.00522
CHD6 chromodomain helicase DNA binding protein 6 2.00469
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 2.00392
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 2.00365
EMX1 empty spiracles homeobox 1 2.00339
RAD54L RAD54-like (S. cerevisiae) 2.00255
CHRM5 cholinergic receptor, muscarinic 5 2.00232
PLA2R1 phospholipase A2 receptor 1, 180kDa 2.00185
DIPK2B divergent protein kinase domain 2B 2.00078
FSHR follicle stimulating hormone receptor 2.00033
DGCR8 DGCR8 microprocessor complex subunit 2.00017

decreased expression

Symbol Name Standardized Value
CAB39 calcium binding protein 39 -5.28461
CDC25B cell division cycle 25B -4.5293
HMG20B high mobility group 20B -3.82098
TUBB6 tubulin, beta 6 class V -3.76517
BASP1 brain abundant, membrane attached signal protein 1 -3.70807
CD81 CD81 molecule -3.68874
NPDC1 neural proliferation, differentiation and control, 1 -3.47515
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -3.332
PCDHB16 protocadherin beta 16 -3.22295
CCNB1 cyclin B1 -3.15801
VAT1 vesicle amine transport 1 -3.06961
KCNK1 potassium channel, two pore domain subfamily K, member 1 -2.97354
TES testin LIM domain protein -2.88871
KRT14 keratin 14, type I -2.74418
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 -2.6183
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -2.54449
COPZ1 coatomer protein complex, subunit zeta 1 -2.53212
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) -2.49433
LAGE3 L antigen family, member 3 -2.48719
SACS sacsin molecular chaperone -2.48454
SPRR2B small proline-rich protein 2B -2.40642
RPL39L ribosomal protein L39-like -2.40341
OXSR1 oxidative stress responsive 1 -2.37311
ANXA2 annexin A2 -2.32002
RPH3AL rabphilin 3A-like (without C2 domains) -2.31691
MICU2 mitochondrial calcium uptake 2 -2.3125
PRKCH protein kinase C, eta -2.29557
MGST3 microsomal glutathione S-transferase 3 -2.27555
KCTD5 potassium channel tetramerization domain containing 5 -2.25763
REXO2 RNA exonuclease 2 -2.25258
S100A11 S100 calcium binding protein A11 -2.24992
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.22551
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.19863
AFG3L2 AFG3-like AAA ATPase 2 -2.19575
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -2.19056
CAPNS1 calpain, small subunit 1 -2.17827
RSRC1 arginine/serine-rich coiled-coil 1 -2.17625
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 -2.17493
S100A10 S100 calcium binding protein A10 -2.16796
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -2.16529
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 -2.15924
DENR density-regulated protein -2.1339
GLOD4 glyoxalase domain containing 4 -2.13317
SHOC2 soc-2 suppressor of clear homolog (C. elegans) -2.10364
TRIP12 thyroid hormone receptor interactor 12 -2.09668
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -2.0956
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.09037
RABAC1 Rab acceptor 1 (prenylated) -2.0786
CCNB2 cyclin B2 -2.06126
NPC2 Niemann-Pick disease, type C2 -2.05385
BLVRA biliverdin reductase A -2.04336
MTMR6 myotubularin related protein 6 -2.04011
ANO10 anoctamin 10 -2.03631
ANXA5 annexin A5 -2.03418
ZNF106 zinc finger protein 106 -2.01232
UBE2C ubiquitin-conjugating enzyme E2C -2.01207
CDC42SE1 CDC42 small effector 1 -2.00586