CRCGN017_MCF10A.TP53.M_24H:O18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dichlorvos 11.26 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:O18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GARRE1 granule associated Rac and RHOG effector 1 5.95173
ACLY ATP citrate lyase 3.22137
ACAA1 acetyl-CoA acyltransferase 1 2.78994
FCHO1 FCH domain only 1 2.53344
HOXA10 homeobox A10 2.36832
COQ8A coenzyme Q8A 2.25917
WASHC5 WASH complex subunit 5 2.20413
ARSJ arylsulfatase family, member J 2.15798
RLN1 relaxin 1 2.14945
ARL4C ADP-ribosylation factor-like 4C 2.14234
NTAQ1 N-terminal glutamine amidase 1 2.13785
WDR7 WD repeat domain 7 2.09203
FGF7 fibroblast growth factor 7 2.05721
PYCR3 pyrroline-5-carboxylate reductase 3 2.0504
ELAC1 elaC ribonuclease Z 1 2.00842
DENND2D DENN/MADD domain containing 2D 2.00559

decreased expression

Symbol Name Standardized Value
HSPA8 heat shock 70kDa protein 8 -5.28291
LAP3 leucine aminopeptidase 3 -4.24986
UFM1 ubiquitin-fold modifier 1 -3.01165
SQSTM1 sequestosome 1 -2.46713
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 -2.278
ANXA2 annexin A2 -2.20981
BASP1 brain abundant, membrane attached signal protein 1 -2.0304
HAT1 histone acetyltransferase 1 -2.00165