CRCGN017_MCF10A.TP53.M_24H:O19 Gene Set
Genes
43 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:O19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HYOU1
|
hypoxia up-regulated 1
|
4.49825
|
|
SLC35A1
|
solute carrier family 35 (CMP-sialic acid transporter), member A1
|
3.55235
|
|
MMP1
|
matrix metallopeptidase 1
|
3.50136
|
|
COMP
|
cartilage oligomeric matrix protein
|
3.28216
|
|
ABHD4
|
abhydrolase domain containing 4
|
3.24403
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
3.10825
|
|
MAP7
|
microtubule-associated protein 7
|
2.90933
|
|
WDR7
|
WD repeat domain 7
|
2.90193
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
2.75104
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
2.60275
|
|
GRB7
|
growth factor receptor-bound protein 7
|
2.41972
|
|
SH3TC2
|
SH3 domain and tetratricopeptide repeats 2
|
2.31783
|
|
PLA2G15
|
phospholipase A2, group XV
|
2.30846
|
|
LGMN
|
legumain
|
2.19785
|
|
NDST2
|
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
|
2.19072
|
|
PGAP4
|
post-GPI attachment to proteins GalNAc transferase 4
|
2.10852
|
|
GNG13
|
guanine nucleotide binding protein (G protein), gamma 13
|
2.07948
|
|
PLA2G7
|
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
|
2.07251
|
|
PLEKHH3
|
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
|
2.06809
|
|
HBB
|
hemoglobin, beta
|
2.06494
|
|
ATP6V1B1
|
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
|
2.06086
|
|
PCDHA9
|
protocadherin alpha 9
|
2.05297
|
|
DDR1
|
discoidin domain receptor tyrosine kinase 1
|
2.04629
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
2.03148
|
|
ZNF304
|
zinc finger protein 304
|
2.018
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.98367
|
|
HMG20B
|
high mobility group 20B
|
-3.25278
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.11896
|
|
UFM1
|
ubiquitin-fold modifier 1
|
-3.07643
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-2.42603
|
|
LPGAT1
|
lysophosphatidylglycerol acyltransferase 1
|
-2.40989
|
|
DYNLRB1
|
dynein, light chain, roadblock-type 1
|
-2.38598
|
|
VPS4A
|
vacuolar protein sorting 4 homolog A (S. cerevisiae)
|
-2.29387
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
-2.26374
|
|
PSMG1
|
proteasome (prosome, macropain) assembly chaperone 1
|
-2.22159
|
|
DLGAP3
|
discs, large (Drosophila) homolog-associated protein 3
|
-2.1927
|
|
WWC3
|
WWC family member 3
|
-2.06825
|
|
WASF2
|
WAS protein family, member 2
|
-2.05081
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
-2.04601
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
-2.02393
|
|
TOMM20
|
translocase of outer mitochondrial membrane 20 homolog (yeast)
|
-2.0116
|
|
UQCR10
|
ubiquinol-cytochrome c reductase, complex III subunit X
|
-2.00655
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
-2.00496
|