CRCGN017_MCF10A.TP53.M_24H:P05 Gene Set
Genes
55 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:P05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CNRIP1
|
cannabinoid receptor interacting protein 1
|
4.35829
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
3.7599
|
|
INSIG1
|
insulin induced gene 1
|
3.39582
|
|
RBKS
|
ribokinase
|
3.27077
|
|
SLC2A6
|
solute carrier family 2 (facilitated glucose transporter), member 6
|
3.12545
|
|
ZNF451
|
zinc finger protein 451
|
3.07189
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
2.786
|
|
ELOVL6
|
ELOVL fatty acid elongase 6
|
2.60376
|
|
SH3D19
|
SH3 domain containing 19
|
2.53796
|
|
TMEM97
|
transmembrane protein 97
|
2.52751
|
|
PRAF2
|
PRA1 domain family, member 2
|
2.41843
|
|
AGR2
|
anterior gradient 2
|
2.38228
|
|
PROS1
|
protein S (alpha)
|
2.37959
|
|
SQSTM1
|
sequestosome 1
|
2.30323
|
|
NME3
|
NME/NM23 nucleoside diphosphate kinase 3
|
2.2642
|
|
SREBF1
|
sterol regulatory element binding transcription factor 1
|
2.24614
|
|
ACLY
|
ATP citrate lyase
|
2.17982
|
|
S100A4
|
S100 calcium binding protein A4
|
2.16524
|
|
FBXO11
|
F-box protein 11
|
2.13935
|
|
HMCES
|
5-hydroxymethylcytosine (hmC) binding, ES cell-specific
|
2.10748
|
|
FADS2
|
fatty acid desaturase 2
|
2.06453
|
|
DTD1
|
D-tyrosyl-tRNA deacylase 1
|
2.01143
|
|
NCK1
|
NCK adaptor protein 1
|
2.00772
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.732
|
|
GNAS
|
GNAS complex locus
|
-4.16128
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.15709
|
|
CYCS
|
cytochrome c, somatic
|
-3.45219
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
-3.02562
|
|
CALM2
|
calmodulin 2 (phosphorylase kinase, delta)
|
-2.91523
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.91097
|
|
HMGN2
|
high mobility group nucleosomal binding domain 2
|
-2.61791
|
|
TOR1A
|
torsin family 1, member A (torsin A)
|
-2.57566
|
|
COG7
|
component of oligomeric golgi complex 7
|
-2.51044
|
|
ATP5PF
|
ATP synthase peripheral stalk subunit F6
|
-2.47054
|
|
ADGRF5
|
adhesion G protein-coupled receptor F5
|
-2.35133
|
|
VBP1
|
von Hippel-Lindau binding protein 1
|
-2.34017
|
|
ZNF274
|
zinc finger protein 274
|
-2.30533
|
|
RPL38
|
ribosomal protein L38
|
-2.27758
|
|
AOC3
|
amine oxidase, copper containing 3
|
-2.25514
|
|
MTARC1
|
mitochondrial amidoxime reducing component 1
|
-2.23971
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.22615
|
|
LHX2
|
LIM homeobox 2
|
-2.21557
|
|
LAMP3
|
lysosomal-associated membrane protein 3
|
-2.19203
|
|
CANT1
|
calcium activated nucleotidase 1
|
-2.16776
|
|
FOXM1
|
forkhead box M1
|
-2.16494
|
|
A2M
|
alpha-2-macroglobulin
|
-2.15896
|
|
MSN
|
moesin
|
-2.13759
|
|
NELFCD
|
negative elongation factor complex member C/D
|
-2.13631
|
|
DUSP9
|
dual specificity phosphatase 9
|
-2.13514
|
|
TUBA1C
|
tubulin, alpha 1c
|
-2.10688
|
|
F8A2
|
coagulation factor VIII-associated 2
|
-2.06497
|
|
EIF2B2
|
eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
|
-2.05584
|
|
TUBA1B
|
tubulin, alpha 1b
|
-2.0544
|
|
ND5
|
NADH dehydrogenase subunit 5
|
-2.05161
|
|
SMC1A
|
structural maintenance of chromosomes 1A
|
-2.04363
|
