CRCGN017_MCF10A.TP53.M_24H:P07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description procarbazine 98.86 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

38 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:P07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 5.33237
CNPY3 canopy FGF signaling regulator 3 5.32398
SNAP25 synaptosomal-associated protein, 25kDa 4.6781
RBP4 retinol binding protein 4, plasma 3.52599
STMN2 stathmin 2 3.31623
ACAA1 acetyl-CoA acyltransferase 1 3.06029
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2.87712
PTGDS prostaglandin D2 synthase 21kDa (brain) 2.53154
SYN1 synapsin I 2.47643
SNAP91 synaptosomal-associated protein, 91kDa 2.41203
ARID5B AT rich interactive domain 5B (MRF1-like) 2.39907
NEFM neurofilament, medium polypeptide 2.36468
CEP57 centrosomal protein 57kDa 2.34778
SV2B synaptic vesicle glycoprotein 2B 2.33307
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 2.25897
RPH3A rabphilin 3A 2.24783
NSG2 neuronal vesicle trafficking associated 2 2.22801
MRPS15 mitochondrial ribosomal protein S15 2.20832
SRSF8 serine/arginine-rich splicing factor 8 2.19338
HLA-DMB major histocompatibility complex, class II, DM beta 2.09941
ADSS2 adenylosuccinate synthase 2 2.03509
AOPEP aminopeptidase O (putative) 2.02764
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 2.00381

decreased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 -4.8034
HAT1 histone acetyltransferase 1 -4.77784
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.20735
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.75892
CANT1 calcium activated nucleotidase 1 -3.35161
MACF1 microtubule-actin crosslinking factor 1 -2.8218
TCTA T-cell leukemia translocation altered -2.50598
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 -2.32705
MSN moesin -2.2831
MTFR1 mitochondrial fission regulator 1 -2.27797
MRPL35 mitochondrial ribosomal protein L35 -2.17695
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -2.16252
COG7 component of oligomeric golgi complex 7 -2.12861
GASK1B golgi associated kinase 1B -2.11261
KDM3A lysine (K)-specific demethylase 3A -2.00898