CRCGN017_MCF10A.TP53.M_24H:P08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description procarbazine 32.95 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:P08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
LGMN legumain 5.33974
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 5.32156
DENND2D DENN/MADD domain containing 2D 3.88203
TXNL4B thioredoxin-like 4B 3.66727
C5 complement component 5 2.94757
FBXL12 F-box and leucine-rich repeat protein 12 2.79546
PRR7 proline rich 7 (synaptic) 2.57931
SLC10A3 solute carrier family 10, member 3 2.47072
FCHO1 FCH domain only 1 2.17587
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 2.09538
KLHL9 kelch-like family member 9 2.05833
TEX10 testis expressed 10 2.03802

decreased expression

Symbol Name Standardized Value
NGRN neugrin, neurite outgrowth associated -3.91613
CD320 CD320 molecule -2.83316
CBR3 carbonyl reductase 3 -2.77266
MSMO1 methylsterol monooxygenase 1 -2.74371
DCK deoxycytidine kinase -2.50338
PRCP prolylcarboxypeptidase (angiotensinase C) -2.45314
HMG20B high mobility group 20B -2.35685
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.2014
KLHL21 kelch-like family member 21 -2.09183
RTF2 replication termination factor 2 -2.01294