CRCGN017_MCF10A.TP53.M_24H:P09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description procarbazine 10.98 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

32 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:P09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 3.6
AGR2 anterior gradient 2 3.4228
LGMN legumain 3.38593
MEF2C myocyte enhancer factor 2C 3.31059
BMP4 bone morphogenetic protein 4 3.24597
SRC SRC proto-oncogene, non-receptor tyrosine kinase 3.2387
MICALL1 MICAL-like 1 2.94265
UBQLN2 ubiquilin 2 2.91097
MAMLD1 mastermind-like domain containing 1 2.8625
MAST2 microtubule associated serine/threonine kinase 2 2.66088
KLHL9 kelch-like family member 9 2.49867
BACE2 beta-site APP-cleaving enzyme 2 2.4625
HYOU1 hypoxia up-regulated 1 2.32613
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 2.28012
TNNI2 troponin I type 2 (skeletal, fast) 2.20183
CERK ceramide kinase 2.19373
ACAA1 acetyl-CoA acyltransferase 1 2.09555
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 2.0936
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.06163
MYBPC1 myosin binding protein C, slow type 2.05117
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.01333

decreased expression

Symbol Name Standardized Value
KIF14 kinesin family member 14 -3.51293
COG2 component of oligomeric golgi complex 2 -3.40543
BAG3 BCL2-associated athanogene 3 -3.04573
PUF60 poly-U binding splicing factor 60KDa -3.03403
FABP5 fatty acid binding protein 5 (psoriasis-associated) -2.99923
BASP1 brain abundant, membrane attached signal protein 1 -2.8897
PCNA proliferating cell nuclear antigen -2.78847
NUSAP1 nucleolar and spindle associated protein 1 -2.3425
NGRN neugrin, neurite outgrowth associated -2.13403
MTFR1 mitochondrial fission regulator 1 -2.13162
ADIPOR1 adiponectin receptor 1 -2.02397