CRCGN017_MCF10A.TP53.M_24H:P13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description cyclophosphamide 101.35 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:P13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KLHL21 kelch-like family member 21 4.8336
FGFR4 fibroblast growth factor receptor 4 3.59092
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.79524
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.51858
BAMBI BMP and activin membrane-bound inhibitor 2.33121
CNRIP1 cannabinoid receptor interacting protein 1 2.21107
FIP1L1 factor interacting with PAPOLA and CPSF1 2.06331

decreased expression

Symbol Name Standardized Value
ACOT9 acyl-CoA thioesterase 9 -4.79909
ADI1 acireductone dioxygenase 1 -4.42606
KIF20A kinesin family member 20A -4.12592
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -3.60593
UFM1 ubiquitin-fold modifier 1 -3.51495
TCTA T-cell leukemia translocation altered -3.03856
ACY1 aminoacylase 1 -2.02781