| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | benzo[k]fluoranthene 100.99 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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52 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:P22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HBA1 | hemoglobin, alpha 1 | 7.29969 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.36923 |
| SPAG4 | sperm associated antigen 4 | 4.73749 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 3.89375 |
| FZD1 | frizzled class receptor 1 | 3.77239 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 3.61824 |
| SNX11 | sorting nexin 11 | 3.33913 |
| HBB | hemoglobin, beta | 3.29906 |
| OLFML2B | olfactomedin-like 2B | 3.18923 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 2.83273 |
| RBP4 | retinol binding protein 4, plasma | 2.81273 |
| MYL9 | myosin, light chain 9, regulatory | 2.52958 |
| DENND2D | DENN/MADD domain containing 2D | 2.42436 |
| CAPN1 | calpain 1, (mu/I) large subunit | 2.32753 |
| STK10 | serine/threonine kinase 10 | 2.26011 |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) | 2.19845 |
| CRLF3 | cytokine receptor-like factor 3 | 2.17444 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 2.17263 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 2.15547 |
| DHDDS | dehydrodolichyl diphosphate synthase | 2.14864 |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | 2.14212 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 | 2.1153 |
| SRP9 | signal recognition particle 9kDa | 2.0963 |
| LYZ | lysozyme | 2.08991 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 2.05418 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 2.0394 |
| EBF2 | early B-cell factor 2 | 2.01809 |
| CRYAB | crystallin, alpha B | 2.00334 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PUF60 | poly-U binding splicing factor 60KDa | -5.17106 |
| KIF14 | kinesin family member 14 | -4.94049 |
| NVL | nuclear VCP-like | -3.75803 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.49378 |
| SCRIB | scribbled planar cell polarity protein | -3.30653 |
| COPS7A | COP9 signalosome subunit 7A | -3.2876 |
| GPAA1 | glycosylphosphatidylinositol anchor attachment 1 | -2.34318 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) | -2.33676 |
| CBX8 | chromobox homolog 8 | -2.3358 |
| SOX5 | SRY (sex determining region Y)-box 5 | -2.32308 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -2.25552 |
| PFN1 | profilin 1 | -2.25501 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | -2.21744 |
| FLT4 | fms-related tyrosine kinase 4 | -2.20076 |
| AKR1D1 | aldo-keto reductase family 1, member D1 | -2.18141 |
| FABP1 | fatty acid binding protein 1, liver | -2.15134 |
| EXOSC4 | exosome component 4 | -2.14708 |
| SPAG6 | sperm associated antigen 6 | -2.12087 |
| ITGB1BP2 | integrin beta 1 binding protein (melusin) 2 | -2.07853 |
| BCHE | butyrylcholinesterase | -2.06022 |
| ATF7 | activating transcription factor 7 | -2.05998 |
| ZNF7 | zinc finger protein 7 | -2.04523 |
| PRUNE2 | prune homolog 2 (Drosophila) | -2.03159 |
| PIK3C2G | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma | -2.00223 |
