| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,3',4,4'-tetrachloro-1,1'-biphenyl 102.01 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
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50 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:A10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CCDC92 | coiled-coil domain containing 92 | 5.2841 |
| ABHD6 | abhydrolase domain containing 6 | 5.03702 |
| FKBP14 | FK506 binding protein 14, 22 kDa | 4.6179 |
| SPAG4 | sperm associated antigen 4 | 4.1096 |
| COL11A1 | collagen, type XI, alpha 1 | 3.94357 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 3.75275 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 3.48067 |
| OLFML2B | olfactomedin-like 2B | 3.328 |
| WIF1 | WNT inhibitory factor 1 | 3.14935 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 2.9673 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.9023 |
| PRRX1 | paired related homeobox 1 | 2.52215 |
| NAP1L3 | nucleosome assembly protein 1-like 3 | 2.44685 |
| TENM3 | teneurin transmembrane protein 3 | 2.4448 |
| RIOX1 | ribosomal oxygenase 1 | 2.39265 |
| ECD | ecdysoneless homolog (Drosophila) | 2.3811 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 2.2429 |
| RGS18 | regulator of G-protein signaling 18 | 2.2117 |
| URGCP | upregulator of cell proliferation | 2.14445 |
| PUS1 | pseudouridylate synthase 1 | 2.1335 |
| CADM1 | cell adhesion molecule 1 | 2.12908 |
| CCL21 | chemokine (C-C motif) ligand 21 | 2.04585 |
| FMOD | fibromodulin | 2.0333 |
| VPREB3 | pre-B lymphocyte 3 | 2.0302 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UFM1 | ubiquitin-fold modifier 1 | -4.5011 |
| PRPF4 | pre-mRNA processing factor 4 | -4.111 |
| TCTA | T-cell leukemia translocation altered | -4.0439 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -3.93247 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -3.66127 |
| BAD | BCL2-associated agonist of cell death | -2.5591 |
| NGRN | neugrin, neurite outgrowth associated | -2.55875 |
| GOLGA1 | golgin A1 | -2.54663 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -2.49065 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -2.48215 |
| BSPRY | B-box and SPRY domain containing | -2.40085 |
| UBAP1 | ubiquitin associated protein 1 | -2.35445 |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit | -2.35 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -2.3359 |
| CRIPT | cysteine-rich PDZ-binding protein | -2.2946 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | -2.22585 |
| TSTD2 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 | -2.17235 |
| CHMP5 | charged multivesicular body protein 5 | -2.1468 |
| ABITRAM | actin binding transcription modulator | -2.11355 |
| RALGDS | ral guanine nucleotide dissociation stimulator | -2.11182 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | -2.1095 |
| TZMP1 | transition zone microprotein 1 | -2.07395 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 | -2.0355 |
| WHR1 | winged helix repair factor 1 | -2.02602 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -2.0228 |
| NAA35 | N(alpha)-acetyltransferase 35, NatC auxiliary subunit | -2.00505 |