| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | pyocyanin 11.11 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
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116 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:A15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 6.11415 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 5.9617 |
| KLHL21 | kelch-like family member 21 | 5.1678 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 5.10895 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.9461 |
| WIF1 | WNT inhibitory factor 1 | 4.72865 |
| STXBP1 | syntaxin binding protein 1 | 3.7583 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 3.47365 |
| STAP2 | signal transducing adaptor family member 2 | 3.35865 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 3.2921 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 3.26645 |
| TXNRD1 | thioredoxin reductase 1 | 3.24075 |
| WASHC5 | WASH complex subunit 5 | 3.14935 |
| BMP2 | bone morphogenetic protein 2 | 3.01797 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 2.92103 |
| ISOC1 | isochorismatase domain containing 1 | 2.89945 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 2.7474 |
| ALAS1 | 5'-aminolevulinate synthase 1 | 2.66625 |
| CADM1 | cell adhesion molecule 1 | 2.63748 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 2.58335 |
| FRS2 | fibroblast growth factor receptor substrate 2 | 2.5815 |
| RSU1 | Ras suppressor protein 1 | 2.56045 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.54965 |
| MFAP2 | microfibrillar-associated protein 2 | 2.5357 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.4815 |
| AURKB | aurora kinase B | 2.47415 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 2.42683 |
| TGFB3 | transforming growth factor, beta 3 | 2.341 |
| FST | follistatin | 2.33187 |
| CREB1 | cAMP responsive element binding protein 1 | 2.30643 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 2.2909 |
| MFAP4 | microfibrillar-associated protein 4 | 2.28915 |
| DFFA | DNA fragmentation factor, 45kDa, alpha polypeptide | 2.2697 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 2.2598 |
| SPHK1 | sphingosine kinase 1 | 2.2403 |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 | 2.22535 |
| LAMA2 | laminin, alpha 2 | 2.21568 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | 2.2017 |
| CBR1 | carbonyl reductase 1 | 2.19425 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 2.15155 |
| SNX7 | sorting nexin 7 | 2.15095 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 2.1411 |
| LAMB3 | laminin, beta 3 | 2.1409 |
| TUBB6 | tubulin, beta 6 class V | 2.11725 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) | 2.10035 |
| RB1 | retinoblastoma 1 | 2.0942 |
| SETBP1 | SET binding protein 1 | 2.079 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 2.071 |
| LOC102724428 | serine/threonine-protein kinase SIK1 | 2.0671 |
| RHOBTB2 | Rho-related BTB domain containing 2 | 2.04595 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 2.03315 |
| STUM | stum, mechanosensory transduction mediator homolog | 2.03055 |
| CDA | cytidine deaminase | 2.0263 |
| SCRN1 | secernin 1 | 2.01745 |
| SFTPB | surfactant protein B | 2.01682 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) | 2.01395 |
| CCNL2 | cyclin L2 | 2.00825 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD81 | CD81 molecule | -5.7759 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -5.5542 |
| TES | testin LIM domain protein | -5.47278 |
| CCNB1 | cyclin B1 | -4.929 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | -4.5188 |
| THAP11 | THAP domain containing 11 | -4.4959 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -3.8058 |
| PRCP | prolylcarboxypeptidase (angiotensinase C) | -3.75715 |
| TMEM50A | transmembrane protein 50A | -3.6798 |
| DIPK1A | divergent protein kinase domain 1A | -3.54857 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.3759 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -3.2432 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -3.1858 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -2.9676 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) | -2.8951 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.8207 |
| REPIN1 | replication initiator 1 | -2.78415 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | -2.7264 |
| GALNT15 | polypeptide N-acetylgalactosaminyltransferase 15 | -2.63985 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 | -2.62945 |
| HSPA1A | heat shock 70kDa protein 1A | -2.5039 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -2.49855 |
| PRAF2 | PRA1 domain family, member 2 | -2.479 |
| CSPG5 | chondroitin sulfate proteoglycan 5 (neuroglycan C) | -2.4132 |
| ZNF76 | zinc finger protein 76 | -2.3475 |
| KLRC1 | killer cell lectin-like receptor subfamily C, member 1 | -2.34185 |
| ZNF580 | zinc finger protein 580 | -2.3102 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 | -2.29715 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -2.2882 |
| BAD | BCL2-associated agonist of cell death | -2.28305 |
| CGREF1 | cell growth regulator with EF-hand domain 1 | -2.2826 |
| NLRP4 | NLR family, pyrin domain containing 4 | -2.28155 |
| ANKRD55 | ankyrin repeat domain 55 | -2.27195 |
| CAMLG | calcium modulating ligand | -2.26685 |
| HTN3 | histatin 3 | -2.2501 |
| NFIL3 | nuclear factor, interleukin 3 regulated | -2.2304 |
| SNTG1 | syntrophin, gamma 1 | -2.2237 |
| OMG | oligodendrocyte myelin glycoprotein | -2.21695 |
| CDC20 | cell division cycle 20 | -2.1975 |
| ARF5 | ADP-ribosylation factor 5 | -2.1914 |
| PHKB | phosphorylase kinase, beta | -2.18033 |
| CCNB2 | cyclin B2 | -2.17895 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -2.1654 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 | -2.1621 |
| DNM1 | dynamin 1 | -2.15605 |
| FAM50B | family with sequence similarity 50, member B | -2.1484 |
| RNFT2 | ring finger protein, transmembrane 2 | -2.14092 |
| GSTK1 | glutathione S-transferase kappa 1 | -2.13845 |
| TENT5C | terminal nucleotidyltransferase 5C | -2.1325 |
| WASHC4 | WASH complex subunit 4 | -2.13248 |
| BID | BH3 interacting domain death agonist | -2.1308 |
| MAGED4B | melanoma antigen family D4B | -2.123 |
| BBS10 | Bardet-Biedl syndrome 10 | -2.1171 |
| ZDHHC7 | zinc finger, DHHC-type containing 7 | -2.10955 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | -2.09177 |
| ASTN1 | astrotactin 1 | -2.08285 |
| DPF1 | D4, zinc and double PHD fingers family 1 | -2.07315 |
| ARL6IP4 | ADP-ribosylation factor-like 6 interacting protein 4 | -2.06375 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -2.03145 |
