CRCGN017_MCF10A.WT.HP_24H:A19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dibenzo[a,l]pyrene 97.23 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:A19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ZW10 zw10 kinetochore protein 5.25135
GATA2 GATA binding protein 2 4.97335
GPER1 G protein-coupled estrogen receptor 1 4.41327
MAP7 microtubule-associated protein 7 4.14237
FCHO1 FCH domain only 1 3.43055
TGFB3 transforming growth factor, beta 3 3.36915
GATA3 GATA binding protein 3 2.98923
MSRA methionine sulfoxide reductase A 2.55145
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.49735
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 2.40495
MAP2K5 mitogen-activated protein kinase kinase 5 2.20802
MICALL1 MICAL-like 1 2.14585
CADM1 cell adhesion molecule 1 2.0846
GET1 guided entry of tail-anchored proteins factor 1 2.0358
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.0108

decreased expression

Symbol Name Standardized Value
TXNDC9 thioredoxin domain containing 9 -4.79485
NUP93 nucleoporin 93kDa -4.7206
STXBP2 syntaxin binding protein 2 -4.3812
NGRN neugrin, neurite outgrowth associated -4.3659
S100A8 S100 calcium binding protein A8 -3.41935
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.85195
GDF15 growth differentiation factor 15 -2.81665
PPIE peptidylprolyl isomerase E (cyclophilin E) -2.66695
CD81 CD81 molecule -2.34855
MT2A metallothionein 2A -2.13665
SCAND1 SCAN domain containing 1 -2.0995
STMN1 stathmin 1 -2.07285
STARD7 StAR-related lipid transfer (START) domain containing 7 -2.0228
EIF5B eukaryotic translation initiation factor 5B -2.00136