CRCGN017_MCF10A.WT.HP_24H:A24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ammonium-perfluorocaprylate 11.0 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

46 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:A24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGR2 anterior gradient 2 5.5379
CNRIP1 cannabinoid receptor interacting protein 1 4.8509
OLFML2B olfactomedin-like 2B 4.83675
ADRB2 adrenoceptor beta 2, surface 3.43645
BCL7B B-cell CLL/lymphoma 7B 3.02215
CCNF cyclin F 2.90048
PLS1 plastin 1 2.67755
TBC1D10C TBC1 domain family, member 10C 2.53695
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.3801
FZD7 frizzled class receptor 7 2.2962
BIRC2 baculoviral IAP repeat containing 2 2.22515
BUD31 BUD31 homolog (S. cerevisiae) 2.1156
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 2.1135
EPHA3 EPH receptor A3 2.11035
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 2.05665
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 2.0133

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -5.5174
HMG20B high mobility group 20B -4.89773
S100A8 S100 calcium binding protein A8 -4.713
KIF14 kinesin family member 14 -4.60775
MAPK13 mitogen-activated protein kinase 13 -4.5126
FKBP4 FK506 binding protein 4, 59kDa -4.39738
RNF167 ring finger protein 167 -4.2993
UBE3C ubiquitin protein ligase E3C -4.07365
SGK1 serum/glucocorticoid regulated kinase 1 -3.61325
MT2A metallothionein 2A -3.58675
DCK deoxycytidine kinase -2.7715
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -2.7044
TRIB3 tribbles pseudokinase 3 -2.5525
TENT4A terminal nucleotidyltransferase 4A -2.4892
RAI14 retinoic acid induced 14 -2.46355
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.33245
NT5DC3 5'-nucleotidase domain containing 3 -2.2619
NCSTN nicastrin -2.22955
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.22942
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 -2.22075
NVL nuclear VCP-like -2.18825
KNTC1 kinetochore associated 1 -2.1871
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.1776
ABHD3 abhydrolase domain containing 3 -2.1576
MFSD12 major facilitator superfamily domain containing 12 -2.14867
MT1X metallothionein 1X -2.08973
LRP2 low density lipoprotein receptor-related protein 2 -2.0744
RAD51AP1 RAD51 associated protein 1 -2.06425
HOXD1 homeobox D1 -2.0247
CA2 carbonic anhydrase II -2.01365