CRCGN017_MCF10A.WT.HP_24H:B04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:B04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
UBQLN2 ubiquilin 2 3.78964
E2F2 E2F transcription factor 2 3.46271
CXCR4 chemokine (C-X-C motif) receptor 4 3.29009
RAB11FIP2 RAB11 family interacting protein 2 (class I) 3.20008
ARID5B AT rich interactive domain 5B (MRF1-like) 2.54219
STK10 serine/threonine kinase 10 2.28261
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 2.24886
UGDH UDP-glucose 6-dehydrogenase 2.15751
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 2.12933

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -4.79708
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.10273
UBE3C ubiquitin protein ligase E3C -3.94813
RNF167 ring finger protein 167 -3.92362
LDHD lactate dehydrogenase D -3.39673
OXCT1 3-oxoacid CoA transferase 1 -3.31962
S100A8 S100 calcium binding protein A8 -3.29691
SLC35F2 solute carrier family 35, member F2 -3.22806
KIF14 kinesin family member 14 -3.04265
MRPS2 mitochondrial ribosomal protein S2 -2.96491
PRPF4 pre-mRNA processing factor 4 -2.79818
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.71719
MSMO1 methylsterol monooxygenase 1 -2.48297
MAPK13 mitogen-activated protein kinase 13 -2.47131
CLTB clathrin, light chain B -2.44868
KIF20A kinesin family member 20A -2.40735
MT2A metallothionein 2A -2.39495
PFN1 profilin 1 -2.32427
SLC31A1 solute carrier family 31 (copper transporter), member 1 -2.23701
NELFB negative elongation factor complex member B -2.21073
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.11935
PPP6C protein phosphatase 6, catalytic subunit -2.10895
DOLPP1 dolichyldiphosphatase 1 -2.09737
TBC1D13 TBC1 domain family, member 13 -2.08961
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.04919
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.02901
BRD3 bromodomain containing 3 -2.02243