CRCGN017_MCF10A.WT.HP_24H:B05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:B05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 5.4175
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 5.03935
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.41925
MNAT1 MNAT CDK-activating kinase assembly factor 1 4.35385
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.1727
PECR peroxisomal trans-2-enoyl-CoA reductase 3.5172
TRIM13 tripartite motif containing 13 3.46835
ARID5B AT rich interactive domain 5B (MRF1-like) 3.32295
TBX2 T-box 2 3.19853
ACAA1 acetyl-CoA acyltransferase 1 3.13573
PANK4 pantothenate kinase 4 2.6404
ZBTB35 zinc finger and BTB domain containing 35 2.5346
PLS1 plastin 1 2.37575
CEP104 centrosomal protein 104kDa 2.33192
USP6NL USP6 N-terminal like 2.30835
WRAP73 WD repeat containing, antisense to TP73 2.2705
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.22135
HBB hemoglobin, beta 2.21848
CCNE2 cyclin E2 2.1745
LRRC47 leucine rich repeat containing 47 2.17435
NCK2 NCK adaptor protein 2 2.03585
LYRM1 LYR motif containing 1 2.0024

decreased expression

Symbol Name Standardized Value
C2CD5 C2 calcium-dependent domain containing 5 -5.0249
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -5.0
CCNB1 cyclin B1 -4.81075
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -4.66
ETFB electron-transfer-flavoprotein, beta polypeptide -4.16965
UBE2A ubiquitin-conjugating enzyme E2A -2.9101
WASHC4 WASH complex subunit 4 -2.4537
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.4396
FOS FBJ murine osteosarcoma viral oncogene homolog -2.32875
MRPL30 mitochondrial ribosomal protein L30 -2.11545
ACSS3 acyl-CoA synthetase short-chain family member 3 -2.0974
LEFTY2 left-right determination factor 2 -2.00645