CRCGN017_MCF10A.WT.HP_24H:B06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:B06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
LAGE3 L antigen family, member 3 4.01227
NOTCH1 notch 1 3.86926
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 3.31373
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.78722
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.46195
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 2.33216
ZMIZ1 zinc finger, MIZ-type containing 1 2.28014
TENT4A terminal nucleotidyltransferase 4A 2.27862
CERK ceramide kinase 2.25262
MEF2C myocyte enhancer factor 2C 2.24034

decreased expression

Symbol Name Standardized Value
TM9SF3 transmembrane 9 superfamily member 3 -4.62108
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.50853
DERA deoxyribose-phosphate aldolase (putative) -4.0586
HMG20B high mobility group 20B -3.56884
GDF15 growth differentiation factor 15 -3.45809
LYPLA1 lysophospholipase I -3.33706
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.01244
C2CD5 C2 calcium-dependent domain containing 5 -2.9981
ARID4B AT rich interactive domain 4B (RBP1-like) -2.87856
NGRN neugrin, neurite outgrowth associated -2.78787
MSMO1 methylsterol monooxygenase 1 -2.71245
MT2A metallothionein 2A -2.52619
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.08248
ACAA1 acetyl-CoA acyltransferase 1 -2.06584