CRCGN017_MCF10A.WT.HP_24H:B10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-ethyl-n-nitrosourea 107.62 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:B10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 8.9078
VAV1 vav 1 guanine nucleotide exchange factor 2.45245
TRAPPC4 trafficking protein particle complex 4 2.45202
H2AX H2A.X variant histone 2.41405
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.23825
FBXO7 F-box protein 7 2.23405
FASTKD3 FAST kinase domains 3 2.16855
NLRX1 NLR family member X1 2.1291
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.07295
TENT4A terminal nucleotidyltransferase 4A 2.0077

decreased expression

Symbol Name Standardized Value
STXBP2 syntaxin binding protein 2 -5.9503
MRPS16 mitochondrial ribosomal protein S16 -5.0722
TUBB6 tubulin, beta 6 class V -4.81685
COPS7A COP9 signalosome subunit 7A -4.7276
TXNDC9 thioredoxin domain containing 9 -4.6942
BASP1 brain abundant, membrane attached signal protein 1 -4.66275
CD58 CD58 molecule -4.05998
PHKA1 phosphorylase kinase, alpha 1 (muscle) -3.0975
COX5B cytochrome c oxidase subunit Vb -2.40187
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -2.3025
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa -2.29285
LIPT1 lipoyltransferase 1 -2.28635
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) -2.22315
SEC61G Sec61 gamma subunit -2.2132
KLRC3 killer cell lectin-like receptor subfamily C, member 3 -2.21255
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 -2.2004
QTMAN queuosine-tRNA mannosyltransferase -2.14495
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.12343
UNC50 unc-50 homolog (C. elegans) -2.1178
CLIP4 CAP-GLY domain containing linker protein family, member 4 -2.1126
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 -2.0693
AP4M1 adaptor-related protein complex 4, mu 1 subunit -2.0623
SLCO1C1 solute carrier organic anion transporter family, member 1C1 -2.04205
MBD5 methyl-CpG binding domain protein 5 -2.03735