CRCGN017_MCF10A.WT.HP_24H:B11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-ethyl-n-nitrosourea 35.87 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:B11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 5.0765
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 4.8193
SNAP25 synaptosomal-associated protein, 25kDa 4.74485
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 3.2348
STMN2 stathmin 2 3.12483
DHDDS dehydrodolichyl diphosphate synthase 2.90948
NAPSA napsin A aspartic peptidase 2.63613
CLDN1 claudin 1 2.2621
HBB hemoglobin, beta 2.18003
RUNDC3A RUN domain containing 3A 2.05415
PVALB parvalbumin 2.0468
EBF2 early B-cell factor 2 2.0269

decreased expression

Symbol Name Standardized Value
PUF60 poly-U binding splicing factor 60KDa -5.6461
ARID4B AT rich interactive domain 4B (RBP1-like) -5.4594
S100A8 S100 calcium binding protein A8 -5.0
TNIP1 TNFAIP3 interacting protein 1 -4.66275
PHKA1 phosphorylase kinase, alpha 1 (muscle) -3.36145
GDF15 growth differentiation factor 15 -3.35425
KRT14 keratin 14, type I -3.0632
RBM34 RNA binding motif protein 34 -2.85683
CD81 CD81 molecule -2.71885
SEPHS2 selenophosphate synthetase 2 -2.6916
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.55698
BPHL biphenyl hydrolase-like (serine hydrolase) -2.5455
SCRIB scribbled planar cell polarity protein -2.5204
PRAME preferentially expressed antigen in melanoma -2.37025
EIF3H eukaryotic translation initiation factor 3, subunit H -2.3576
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.29422
GGPS1 geranylgeranyl diphosphate synthase 1 -2.2408
ZNF16 zinc finger protein 16 -2.151
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -2.1359
EFNA3 ephrin-A3 -2.13325
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.1135
BCOR BCL6 corepressor -2.0487
TMEM132A transmembrane protein 132A -2.01595
MNX1 motor neuron and pancreas homeobox 1 -2.01075