CRCGN017_MCF10A.WT.HP_24H:B14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description indole 33.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:B14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
OXSR1 oxidative stress responsive 1 5.24115
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 5.13952
ABHD6 abhydrolase domain containing 6 4.76595
AGR2 anterior gradient 2 4.72855
PPARG peroxisome proliferator-activated receptor gamma 4.7215
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 4.53314
PEX11A peroxisomal biogenesis factor 11 alpha 4.17268
TBX2 T-box 2 4.15327
AURKB aurora kinase B 2.02465

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -5.57905
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -5.28897
CCNB2 cyclin B2 -4.7295
RNF167 ring finger protein 167 -3.97075
THAP11 THAP domain containing 11 -3.48635
MVD mevalonate (diphospho) decarboxylase -2.4462
PFN1 profilin 1 -2.38635
HOXA5 homeobox A5 -2.32785
SQLE squalene epoxidase -2.19822
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -2.18782
ACAD10 acyl-CoA dehydrogenase family, member 10 -2.1735
SPACA9 sperm acrosome associated 9 -2.06775
NGRN neugrin, neurite outgrowth associated -2.0534
LCN2 lipocalin 2 -2.0102