CRCGN017_MCF10A.WT.HP_24H:B15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description indole 11.11 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:B15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FKBP14 FK506 binding protein 14, 22 kDa 5.3122
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 5.2273
AKT1 v-akt murine thymoma viral oncogene homolog 1 4.88365
SNAP25 synaptosomal-associated protein, 25kDa 4.53005
WIF1 WNT inhibitory factor 1 3.72605
VGLL4 vestigial-like family member 4 3.42803
ACAA1 acetyl-CoA acyltransferase 1 3.26605
AGR2 anterior gradient 2 2.6954
GRB10 growth factor receptor-bound protein 10 2.52588
BACE2 beta-site APP-cleaving enzyme 2 2.5187
ZBTB35 zinc finger and BTB domain containing 35 2.39917
PLS1 plastin 1 2.1931

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -5.0
SGK1 serum/glucocorticoid regulated kinase 1 -4.76595
CHMP4B charged multivesicular body protein 4B -4.34797
KRT14 keratin 14, type I -3.45915
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.37483
NGRN neugrin, neurite outgrowth associated -2.66095
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.5421
DCK deoxycytidine kinase -2.306
WASHC4 WASH complex subunit 4 -2.08245
BCORL1 BCL6 corepressor-like 1 -2.0418