CRCGN017_MCF10A.WT.HP_24H:B17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description flutamide 33.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

60 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:B17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
UBQLN2 ubiquilin 2 5.06875
ADGRE5 adhesion G protein-coupled receptor E5 4.84495
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 4.8194
GPER1 G protein-coupled estrogen receptor 1 4.58085
CNRIP1 cannabinoid receptor interacting protein 1 4.0311
MXD1 MAX dimerization protein 1 2.5478
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.47685
WIF1 WNT inhibitory factor 1 2.41485
PLS1 plastin 1 2.3027
EPHA2 EPH receptor A2 2.19155
EMP3 epithelial membrane protein 3 2.1434
ZNF143 zinc finger protein 143 2.0935
WAPL WAPL cohesin release factor 2.01055
CASQ2 calsequestrin 2 (cardiac muscle) 2.0078

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -5.6801
HSPA8 heat shock 70kDa protein 8 -5.50913
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -5.4196
PCCB propionyl CoA carboxylase, beta polypeptide -5.0242
NUP85 nucleoporin 85kDa -4.8291
HOXA5 homeobox A5 -4.6319
HMG20B high mobility group 20B -4.62365
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -4.3384
MRPL58 mitochondrial ribosomal protein L58 -4.056
MRPS7 mitochondrial ribosomal protein S7 -3.80635
SGK1 serum/glucocorticoid regulated kinase 1 -3.60245
TMEM94 transmembrane protein 94 -3.19155
FPGS folylpolyglutamate synthase -3.16395
KCTD2 potassium channel tetramerization domain containing 2 -3.14322
WASHC4 WASH complex subunit 4 -3.01818
CDR2L cerebellar degeneration-related protein 2-like -2.8634
LLGL2 lethal giant larvae homolog 2 (Drosophila) -2.86305
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 -2.79757
CD81 CD81 molecule -2.784
ACAA1 acetyl-CoA acyltransferase 1 -2.7793
SUMO4 small ubiquitin-like modifier 4 -2.67565
NAT9 N-acetyltransferase 9 (GCN5-related, putative) -2.53675
ATF5 activating transcription factor 5 -2.51622
NGRN neugrin, neurite outgrowth associated -2.42635
RTRAF RNA transcription, translation and transport factor -2.3482
ARMC7 armadillo repeat containing 7 -2.297
ATP5PD ATP synthase peripheral stalk subunit d -2.2937
CNIH1 cornichon family AMPA receptor auxiliary protein 1 -2.2923
TRIM68 tripartite motif containing 68 -2.2532
GORASP1 golgi reassembly stacking protein 1, 65kDa -2.25035
MRPL49 mitochondrial ribosomal protein L49 -2.23235
PIGH phosphatidylinositol glycan anchor biosynthesis, class H -2.21975
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.21918
ZNF26 zinc finger protein 26 -2.1716
AP5M1 adaptor-related protein complex 5, mu 1 subunit -2.16635
FDXR ferredoxin reductase -2.1492
GLDC glycine dehydrogenase (decarboxylating) -2.14575
CD82 CD82 molecule -2.12545
LOC124907090 ankyrin repeat domain-containing protein SOWAHC-like -2.12205
UQCRH ubiquinol-cytochrome c reductase hinge protein -2.11785
ZMAT3 zinc finger, matrin-type 3 -2.0811
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -2.0637
HOXB5 homeobox B5 -2.05967
ACYP2 acylphosphatase 2, muscle type -2.04285
BLVRB biliverdin reductase B -2.02155
SASH3 SAM and SH3 domain containing 3 -2.0199