CRCGN017_MCF10A.WT.HP_24H:B22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-aminodiphenyl 98.46 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:B22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 4.9427
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 4.0666
AGR2 anterior gradient 2 3.7783
TBX2 T-box 2 3.71927
CCNA1 cyclin A1 3.2082
RPP38 ribonuclease P/MRP 38kDa subunit 3.15
STAMBP STAM binding protein 2.87885
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.72665
TIMP2 TIMP metallopeptidase inhibitor 2 2.33505
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.27285
SMIM40 small integral membrane protein 40 2.26855
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.07808
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) 2.02675

decreased expression

Symbol Name Standardized Value
TARBP1 TAR (HIV-1) RNA binding protein 1 -10.0
LAP3 leucine aminopeptidase 3 -5.2895
NPDC1 neural proliferation, differentiation and control, 1 -5.20235
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.2165
FPGS folylpolyglutamate synthase -2.92885
FBXO21 F-box protein 21 -2.22357
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.11163
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.00415