CRCGN017_MCF10A.WT.HP_24H:B23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-aminodiphenyl 32.82 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:B23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 4.49417
ADAT1 adenosine deaminase, tRNA-specific 1 4.22345
AGR2 anterior gradient 2 3.66795
WDR7 WD repeat domain 7 2.8967
KDM5D lysine (K)-specific demethylase 5D 2.8628
ZNF589 zinc finger protein 589 2.78772
VMP1 vacuole membrane protein 1 2.77155
PLS1 plastin 1 2.63625
TRAPPC6A trafficking protein particle complex 6A 2.538
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.3696
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.16462
SATB1 SATB homeobox 1 2.1013
PLSCR3 phospholipid scramblase 3 2.0931
FAM114A2 family with sequence similarity 114, member A2 2.018

decreased expression

Symbol Name Standardized Value
CCNB2 cyclin B2 -5.24785
PUF60 poly-U binding splicing factor 60KDa -5.05465
TUBA4A tubulin, alpha 4a -5.0
MAPK13 mitogen-activated protein kinase 13 -4.98155
SNX7 sorting nexin 7 -3.5003
ERC2 ELKS/RAB6-interacting/CAST family member 2 -3.25958
EIF5 eukaryotic translation initiation factor 5 -3.0539
SMC1A structural maintenance of chromosomes 1A -2.81128
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -2.5557
TLCD3A TLC domain containing 3A -2.5281
ACAA1 acetyl-CoA acyltransferase 1 -2.506
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.3727
SCRIB scribbled planar cell polarity protein -2.35735
ELANE elastase, neutrophil expressed -2.30615
MT2A metallothionein 2A -2.29575
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.13195
ZNF7 zinc finger protein 7 -2.1097