| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4-aminodiphenyl 10.94 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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56 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:B24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZW10 | zw10 kinetochore protein | 5.57745 |
| CHMP6 | charged multivesicular body protein 6 | 5.22165 |
| AGR2 | anterior gradient 2 | 4.95195 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 4.779 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | 4.7171 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.63233 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 3.76875 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 3.61137 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 3.3298 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 3.2062 |
| LSR | lipolysis stimulated lipoprotein receptor | 2.7709 |
| ZBTB24 | zinc finger and BTB domain containing 24 | 2.76715 |
| TMEM186 | transmembrane protein 186 | 2.63735 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 2.53268 |
| PTS | 6-pyruvoyltetrahydropterin synthase | 2.4484 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.39855 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 2.31122 |
| OLFML2B | olfactomedin-like 2B | 2.30935 |
| BARD1 | BRCA1 associated RING domain 1 | 2.2673 |
| WIF1 | WNT inhibitory factor 1 | 2.258 |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 2.168 |
| CENPE | centromere protein E, 312kDa | 2.15515 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 2.1379 |
| DEXI | Dexi homolog (mouse) | 2.11035 |
| SCAF8 | SR-related CTD-associated factor 8 | 2.08805 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.07935 |
| MKRN2 | makorin ring finger protein 2 | 2.06725 |
| NEFM | neurofilament, medium polypeptide | 2.06335 |
| TMEM168 | transmembrane protein 168 | 2.05195 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 2.03875 |
| METTL18 | methyltransferase like 18 | 2.03225 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SGK1 | serum/glucocorticoid regulated kinase 1 | -5.75845 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.353 |
| CCDC86 | coiled-coil domain containing 86 | -5.3303 |
| FASTKD5 | FAST kinase domains 5 | -4.80305 |
| KRT14 | keratin 14, type I | -4.684 |
| FKBP4 | FK506 binding protein 4, 59kDa | -4.15965 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.95375 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | -3.9091 |
| GDF15 | growth differentiation factor 15 | -3.8241 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -3.6164 |
| FAIM | Fas apoptotic inhibitory molecule | -3.4333 |
| S100A8 | S100 calcium binding protein A8 | -3.0956 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | -2.47175 |
| WASHC4 | WASH complex subunit 4 | -2.38323 |
| MEN1 | multiple endocrine neoplasia I | -2.36825 |
| CPM | carboxypeptidase M | -2.2811 |
| TMEM140 | transmembrane protein 140 | -2.26185 |
| CAV2 | caveolin 2 | -2.1765 |
| TENT4A | terminal nucleotidyltransferase 4A | -2.1003 |
| SLC28A3 | solute carrier family 28 (concentrative nucleoside transporter), member 3 | -2.1001 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.0758 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | -2.06635 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | -2.05475 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -2.03155 |
| BAD | BCL2-associated agonist of cell death | -2.02567 |
