| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sr1664 10.0 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
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64 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:C07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 3.974 |
| AGR2 | anterior gradient 2 | 3.89105 |
| TBX2 | T-box 2 | 3.83748 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.83428 |
| SQOR | sulfide quinone oxidoreductase | 3.41055 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.22668 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 3.19985 |
| GSAP | gamma-secretase activating protein | 2.97818 |
| HMOX1 | heme oxygenase 1 | 2.97645 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 2.84825 |
| AARS1 | alanyl-tRNA synthetase 1 | 2.8188 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 2.66285 |
| INTS14 | integrator complex subunit 14 | 2.61975 |
| WIF1 | WNT inhibitory factor 1 | 2.58075 |
| PSAT1 | phosphoserine aminotransferase 1 | 2.5485 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 2.4796 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | 2.35185 |
| XPOT | exportin, tRNA | 2.29545 |
| ALAS1 | 5'-aminolevulinate synthase 1 | 2.29525 |
| VSIG2 | V-set and immunoglobulin domain containing 2 | 2.2263 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 | 2.20845 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) | 2.19798 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) | 2.19425 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 2.18265 |
| TRIB3 | tribbles pseudokinase 3 | 2.16295 |
| SLF2 | SMC5-SMC6 complex localization factor 2 | 2.12002 |
| MFAP1 | microfibrillar-associated protein 1 | 2.10815 |
| EVL | Enah/Vasp-like | 2.07595 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 2.05445 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -5.65335 |
| CCDC86 | coiled-coil domain containing 86 | -5.02505 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -4.9181 |
| TXNDC9 | thioredoxin domain containing 9 | -4.6884 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | -4.67243 |
| BID | BH3 interacting domain death agonist | -4.2659 |
| TKT | transketolase | -4.06318 |
| CLTB | clathrin, light chain B | -3.91131 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -3.53202 |
| SAP30L | SAP30-like | -3.49515 |
| LYPLA1 | lysophospholipase I | -3.41593 |
| REPS2 | RALBP1 associated Eps domain containing 2 | -3.0474 |
| BAD | BCL2-associated agonist of cell death | -3.0415 |
| ATG3 | autophagy related 3 | -2.82763 |
| SHPK | sedoheptulokinase | -2.61975 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 | -2.40195 |
| ASRGL1 | asparaginase like 1 | -2.3724 |
| UBFD1 | ubiquitin family domain containing 1 | -2.3396 |
| MALT1 | MALT1 paracaspase | -2.32322 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -2.246 |
| FAIM | Fas apoptotic inhibitory molecule | -2.2448 |
| STMN1 | stathmin 1 | -2.23395 |
| MPDU1 | mannose-P-dolichol utilization defect 1 | -2.1778 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -2.15275 |
| MRPL30 | mitochondrial ribosomal protein L30 | -2.13475 |
| ITGB8 | integrin, beta 8 | -2.10365 |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein | -2.0895 |
| SNX7 | sorting nexin 7 | -2.0436 |
| PLA2G3 | phospholipase A2, group III | -2.04045 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -2.0304 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -2.02995 |
| HOXC8 | homeobox C8 | -2.02765 |
| MRPL15 | mitochondrial ribosomal protein L15 | -2.01605 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | -2.0057 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -2.00365 |
