CRCGN017_MCF10A.WT.HP_24H:C09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sr1664 1.11 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

45 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:C09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ZBTB35 zinc finger and BTB domain containing 35 3.4874
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 3.24008
TSEN2 TSEN2 tRNA splicing endonuclease subunit 3.0736
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.8873
ACAA1 acetyl-CoA acyltransferase 1 2.8625
FGFR2 fibroblast growth factor receptor 2 2.81456
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.7674
CYBC1 cytochrome b-245 chaperone 1 2.4967
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.4459
SLC75A1 solute carrier family 75 member 1 2.3928
COMMD8 COMM domain containing 8 2.38875
RAI14 retinoic acid induced 14 2.3521
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 2.3493
RWDD3 RWD domain containing 3 2.2463
CNRIP1 cannabinoid receptor interacting protein 1 2.21835
CSAG2 CSAG family, member 2 2.1639
VPS33B vacuolar protein sorting 33 homolog B (yeast) 2.1495
MAGEA2B melanoma antigen family A2B 2.1414
ZNF266 zinc finger protein 266 2.1121
SOX12 SRY (sex determining region Y)-box 12 2.10475
RMDN1 regulator of microtubule dynamics 1 2.1002
ZNF195 zinc finger protein 195 2.0776
SGPP1 sphingosine-1-phosphate phosphatase 1 2.05255
MAGEA12 melanoma antigen family A12 2.03845
CLTA clathrin, light chain A 2.0185
ZNF107 zinc finger protein 107 2.0096

decreased expression

Symbol Name Standardized Value
NLRP4 NLR family, pyrin domain containing 4 -5.6836
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -4.72215
SGK1 serum/glucocorticoid regulated kinase 1 -4.5255
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.3673
CD44 CD44 molecule (Indian blood group) -4.30148
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -4.2195
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -3.2416
RALGDS ral guanine nucleotide dissociation stimulator -2.92147
IFRD2 interferon-related developmental regulator 2 -2.7108
PPP6R1 protein phosphatase 6, regulatory subunit 1 -2.53295
PRRC1 proline-rich coiled-coil 1 -2.25225
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.22865
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -2.19225
REEP1 receptor accessory protein 1 -2.18695
RBP1 retinol binding protein 1, cellular -2.09645
KIAA0513 KIAA0513 -2.0513
PLD3 phospholipase D family, member 3 -2.03825
HSPA1A heat shock 70kDa protein 1A -2.03235
S100A8 S100 calcium binding protein A8 -2.01435