| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | lg100268 10.0 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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71 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:C10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 6.19055 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | 5.55045 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.56465 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 4.4958 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 4.37215 |
| TRIB3 | tribbles pseudokinase 3 | 3.72025 |
| PHGDH | phosphoglycerate dehydrogenase | 3.6273 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 3.4835 |
| GARS1 | glycyl-tRNA synthetase 1 | 3.34565 |
| PSAT1 | phosphoserine aminotransferase 1 | 3.32135 |
| AARS1 | alanyl-tRNA synthetase 1 | 3.27695 |
| GLRX | glutaredoxin (thioltransferase) | 3.2081 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 3.13562 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 3.11955 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.07557 |
| FHL2 | four and a half LIM domains 2 | 3.0524 |
| STX1A | syntaxin 1A (brain) | 2.8382 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 | 2.79774 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 2.67935 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | 2.66865 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 2.6156 |
| UPP1 | uridine phosphorylase 1 | 2.558 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 2.34865 |
| TARS1 | threonyl-tRNA synthetase 1 | 2.3353 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 2.3215 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 2.2792 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) | 2.27423 |
| EGR1 | early growth response 1 | 2.25618 |
| MARS1 | methionyl-tRNA synthetase 1 | 2.19053 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 2.18375 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 2.12875 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 2.12317 |
| SARS1 | seryl-tRNA synthetase 1 | 2.11725 |
| LMAN1 | lectin, mannose-binding, 1 | 2.07203 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 2.0689 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.03995 |
| ZNF706 | zinc finger protein 706 | 2.0227 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MSMO1 | methylsterol monooxygenase 1 | -5.27555 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -5.00855 |
| FASTKD5 | FAST kinase domains 5 | -4.99345 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.8424 |
| STK10 | serine/threonine kinase 10 | -4.6372 |
| PMM2 | phosphomannomutase 2 | -4.5046 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | -4.50195 |
| ADRB2 | adrenoceptor beta 2, surface | -2.98415 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.80907 |
| PRR15L | proline rich 15-like | -2.75475 |
| RXYLT1 | ribitol xylosyltransferase 1 | -2.72915 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | -2.7051 |
| BAG1 | BCL2-associated athanogene | -2.5088 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -2.49948 |
| STMN1 | stathmin 1 | -2.48955 |
| MYOG | myogenin (myogenic factor 4) | -2.40495 |
| HOXA5 | homeobox A5 | -2.34525 |
| ALDOC | aldolase C, fructose-bisphosphate | -2.30495 |
| OAZ2 | ornithine decarboxylase antizyme 2 | -2.27795 |
| QTMAN | queuosine-tRNA mannosyltransferase | -2.2727 |
| CD81 | CD81 molecule | -2.2493 |
| MVD | mevalonate (diphospho) decarboxylase | -2.2438 |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 | -2.208 |
| CLN3 | ceroid-lipofuscinosis, neuronal 3 | -2.19392 |
| CTSO | cathepsin O | -2.1851 |
| ZNF263 | zinc finger protein 263 | -2.16945 |
| RALGDS | ral guanine nucleotide dissociation stimulator | -2.13418 |
| ATP12A | ATPase, H+/K+ transporting, nongastric, alpha polypeptide | -2.13355 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -2.11025 |
| PLK2 | polo-like kinase 2 | -2.10575 |
| CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 | -2.09975 |
| IL17B | interleukin 17B | -2.052 |
| BAD | BCL2-associated agonist of cell death | -2.04982 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -2.02595 |
