CRCGN017_MCF10A.WT.HP_24H:C11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description lg100268 3.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

37 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:C11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PLS1 plastin 1 4.59525
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 3.955
ABHD6 abhydrolase domain containing 6 3.81377
ABHD4 abhydrolase domain containing 4 3.06015
OLFML2B olfactomedin-like 2B 2.85425
ACLY ATP citrate lyase 2.69395
TBPL1 TBP-like 1 2.59425
KDM5A lysine (K)-specific demethylase 5A 2.58845
MSRA methionine sulfoxide reductase A 2.11825
PLAC8 placenta-specific 8 2.1129
DPY19L4 dpy-19-like 4 (C. elegans) 2.0041

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -5.0
TES testin LIM domain protein -4.37345
S100A8 S100 calcium binding protein A8 -4.17745
RGS2 regulator of G-protein signaling 2 -3.1819
KRT14 keratin 14, type I -3.06185
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) -2.93435
MAVS mitochondrial antiviral signaling protein -2.72655
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -2.5294
TMEM230 transmembrane protein 230 -2.5009
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.4942
DDRGK1 DDRGK domain containing 1 -2.43185
EPB41L1 erythrocyte membrane protein band 4.1-like 1 -2.34515
CTF1 cardiotrophin 1 -2.34295
ZNF133 zinc finger protein 133 -2.33648
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.32928
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.2883
PANK2 pantothenate kinase 2 -2.2763
STXBP2 syntaxin binding protein 2 -2.26215
DDR1 discoidin domain receptor tyrosine kinase 1 -2.16385
ATRN attractin -2.14878
SNX5 sorting nexin 5 -2.1229
PRSS22 protease, serine, 22 -2.0999
LRRC41 leucine rich repeat containing 41 -2.08407
TM9SF2 transmembrane 9 superfamily member 2 -2.0481
TPD52L1 tumor protein D52-like 1 -2.0319
CRNKL1 crooked neck pre-mRNA splicing factor 1 -2.00815