CRCGN017_MCF10A.WT.HP_24H:C13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description bexarotene 1.0 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:C13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CARMIL1 capping protein regulator and myosin 1 linker 1 4.9495
CERK ceramide kinase 3.9444
TCEA2 transcription elongation factor A (SII), 2 3.26615
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 3.0636
ACAA1 acetyl-CoA acyltransferase 1 3.02793
TBPL1 TBP-like 1 2.8911
PLS1 plastin 1 2.60185
FBXO7 F-box protein 7 2.24025
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.222
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 2.141
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.0933

decreased expression

Symbol Name Standardized Value
TLCD3A TLC domain containing 3A -4.96335
TRAPPC3 trafficking protein particle complex 3 -3.9397
LYPLA1 lysophospholipase I -3.37042
CD81 CD81 molecule -3.08075
TAC4 tachykinin 4 (hemokinin) -2.98245
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.52455
SGK1 serum/glucocorticoid regulated kinase 1 -2.39715
PHKA1 phosphorylase kinase, alpha 1 (muscle) -2.21705
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.1832
DUSP14 dual specificity phosphatase 14 -2.1757
BASP1 brain abundant, membrane attached signal protein 1 -2.0071