| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | bexarotene 0.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:C14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| C2CD2 | C2 calcium-dependent domain containing 2 | 5.26425 |
| CANT1 | calcium activated nucleotidase 1 | 4.4313 |
| PLSCR1 | phospholipid scramblase 1 | 4.3952 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 4.32827 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 4.2128 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 4.05455 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 4.0281 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 3.63018 |
| TCEA2 | transcription elongation factor A (SII), 2 | 3.6282 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | 3.33325 |
| FAIM | Fas apoptotic inhibitory molecule | 3.3274 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.24668 |
| FGFR4 | fibroblast growth factor receptor 4 | 3.23272 |
| THAP12 | THAP domain containing 12 | 3.1347 |
| RSF1 | remodeling and spacing factor 1 | 2.685 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 2.44875 |
| ANO10 | anoctamin 10 | 2.42455 |
| OLFML2B | olfactomedin-like 2B | 2.3256 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | 2.32253 |
| TMEM186 | transmembrane protein 186 | 2.2925 |
| GAB2 | GRB2-associated binding protein 2 | 2.26335 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.25445 |
| CCNE2 | cyclin E2 | 2.21497 |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) | 2.1748 |
| NME1 | NME/NM23 nucleoside diphosphate kinase 1 | 2.16445 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 2.078 |
| FHL2 | four and a half LIM domains 2 | 2.0778 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 2.0449 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 2.02782 |
| CCDC90B | coiled-coil domain containing 90B | 2.02095 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | 2.01305 |
| Symbol | Name | Standardized Value |
|---|---|---|
| STXBP2 | syntaxin binding protein 2 | -4.7413 |
| DSG2 | desmoglein 2 | -4.53215 |
| PRPF4 | pre-mRNA processing factor 4 | -4.12477 |
| GDF15 | growth differentiation factor 15 | -3.84835 |
| MSMO1 | methylsterol monooxygenase 1 | -3.76535 |
| KRT14 | keratin 14, type I | -3.4578 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -3.3353 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -3.2712 |
| COPS7A | COP9 signalosome subunit 7A | -3.04725 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.93053 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -2.90917 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -2.90915 |
| TRIB3 | tribbles pseudokinase 3 | -2.86365 |
| CREB1 | cAMP responsive element binding protein 1 | -2.7828 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -2.6771 |
| ZNF79 | zinc finger protein 79 | -2.49907 |
| RAI14 | retinoic acid induced 14 | -2.47865 |
| S100A1 | S100 calcium binding protein A1 | -2.4233 |
| NGRN | neugrin, neurite outgrowth associated | -2.4189 |
| NOCT | nocturnin | -2.38805 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | -2.23605 |
| PGPEP1 | pyroglutamyl-peptidase I | -2.235 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -2.21285 |
| BAD | BCL2-associated agonist of cell death | -2.20823 |
| JUP | junction plakoglobin | -2.20655 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -2.18665 |
| CBX8 | chromobox homolog 8 | -2.1706 |
| DNM2 | dynamin 2 | -2.1509 |
| TENM1 | teneurin transmembrane protein 1 | -2.1384 |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 | -2.1123 |
| NVL | nuclear VCP-like | -2.04625 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 | -2.04185 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | -2.041 |
| MAVS | mitochondrial antiviral signaling protein | -2.0375 |
| ALAS2 | 5'-aminolevulinate synthase 2 | -2.0279 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 | -2.0165 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 | -2.0104 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -2.00547 |
| TSTD2 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 | -2.00415 |
