CRCGN017_MCF10A.WT.HP_24H:C15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description bexarotene 0.11 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:C15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 5.4527
ABHD6 abhydrolase domain containing 6 4.64302
WASF3 WAS protein family, member 3 4.50145
TCEA2 transcription elongation factor A (SII), 2 4.2141
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.7914
ACAA1 acetyl-CoA acyltransferase 1 3.15865
IGHMBP2 immunoglobulin mu binding protein 2 2.9999
TATDN2 TatD DNase domain containing 2 2.64515
TBPL1 TBP-like 1 2.5346
IFI44L interferon-induced protein 44-like 2.3486
TPD52L2 tumor protein D52-like 2 2.16595
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 2.03385
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.0126

decreased expression

Symbol Name Standardized Value
CHMP4B charged multivesicular body protein 4B -4.7157
FABP5 fatty acid binding protein 5 (psoriasis-associated) -3.59705
ANXA2 annexin A2 -3.25862
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.87215
LYPLA1 lysophospholipase I -2.77638
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.47415
SORBS3 sorbin and SH3 domain containing 3 -2.29757
TLCD3A TLC domain containing 3A -2.2862
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.09492
XK X-linked Kx blood group -2.03575