CRCGN017_MCF10A.WT.HP_24H:C16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acrolein 102.99 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

27 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:C16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCP110 centriolar coiled coil protein 110kDa 5.1179
TXNL4B thioredoxin-like 4B 4.69875
CCL2 chemokine (C-C motif) ligand 2 3.1667
KDM5A lysine (K)-specific demethylase 5A 2.98145
FCHO1 FCH domain only 1 2.77265
PRKCQ protein kinase C, theta 2.7233
TUBA3E tubulin, alpha 3e 2.4074
SART1 squamous cell carcinoma antigen recognized by T cells 2.36715
SLC75A1 solute carrier family 75 member 1 2.3655
TPD52L2 tumor protein D52-like 2 2.30425
TBC1D31 TBC1 domain family, member 31 2.22965
NOSIP nitric oxide synthase interacting protein 2.135
HBB hemoglobin, beta 2.10908
DEF8 differentially expressed in FDCP 8 homolog (mouse) 2.10095
TEX10 testis expressed 10 2.04985
THAP4 THAP domain containing 4 2.0089

decreased expression

Symbol Name Standardized Value
CHIC2 cysteine-rich hydrophobic domain 2 -6.1795
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -4.81075
C2CD5 C2 calcium-dependent domain containing 5 -4.76425
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -3.4616
ARID4B AT rich interactive domain 4B (RBP1-like) -3.22635
MSMO1 methylsterol monooxygenase 1 -3.0205
IFRD2 interferon-related developmental regulator 2 -2.58068
NGRN neugrin, neurite outgrowth associated -2.39285
SGK1 serum/glucocorticoid regulated kinase 1 -2.30275
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.2876
MTERF3 mitochondrial transcription termination factor 3 -2.1053