CRCGN017_MCF10A.WT.HP_24H:C18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acrolein 11.44 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

16 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:C18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCR4 chemokine (C-X-C motif) receptor 4 4.86887
C2CD2 C2 calcium-dependent domain containing 2 4.5736
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 4.05473
ACAA1 acetyl-CoA acyltransferase 1 3.18285
HBB hemoglobin, beta 3.1742
FCHO1 FCH domain only 1 2.22785
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.07075
AARSD1 alanyl-tRNA synthetase domain containing 1 2.04715

decreased expression

Symbol Name Standardized Value
CAB39 calcium binding protein 39 -5.2618
TXNDC9 thioredoxin domain containing 9 -4.7558
ACOT9 acyl-CoA thioesterase 9 -4.68005
CREB1 cAMP responsive element binding protein 1 -3.46537
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.34745
NLRP4 NLR family, pyrin domain containing 4 -3.1812
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.73887
REV1 REV1, polymerase (DNA directed) -2.11785