CRCGN017_MCF10A.WT.HP_24H:D01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description omeprazole 100.0 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

35 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:D01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 4.44153
TXNRD1 thioredoxin reductase 1 4.37071
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 4.04301
COMP cartilage oligomeric matrix protein 3.03251
UGDH UDP-glucose 6-dehydrogenase 2.82345
CCDC92 coiled-coil domain containing 92 2.65658
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.61868
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.50916
CCL2 chemokine (C-C motif) ligand 2 2.42715
GLRX glutaredoxin (thioltransferase) 2.40608
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.34117
FIP1L1 factor interacting with PAPOLA and CPSF1 2.32795
EGR1 early growth response 1 2.29924
ANO1 anoctamin 1, calcium activated chloride channel 2.24584
NUCB2 nucleobindin 2 2.24213
IL13RA1 interleukin 13 receptor, alpha 1 2.15509
HMGA2 high mobility group AT-hook 2 2.11677
GCLM glutamate-cysteine ligase, modifier subunit 2.09965

decreased expression

Symbol Name Standardized Value
CD81 CD81 molecule -3.72463
COG2 component of oligomeric golgi complex 2 -3.71601
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -3.38413
CCNB1 cyclin B1 -3.06984
ADRB2 adrenoceptor beta 2, surface -3.06798
NFIL3 nuclear factor, interleukin 3 regulated -2.87758
ANKRD10 ankyrin repeat domain 10 -2.79447
WASHC4 WASH complex subunit 4 -2.61073
LYPLA1 lysophospholipase I -2.52869
REEP5 receptor accessory protein 5 -2.37389
SGK1 serum/glucocorticoid regulated kinase 1 -2.21258
CREG1 cellular repressor of E1A-stimulated genes 1 -2.18177
TCEAL4 transcription elongation factor A (SII)-like 4 -2.04394
MYOG myogenin (myogenic factor 4) -2.02755
CASZ1 castor zinc finger 1 -2.02498
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.01298
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.00805