CRCGN017_MCF10A.WT.HP_24H:D04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description s26948 10.0 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

32 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:D04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ACAA1 acetyl-CoA acyltransferase 1 4.66053
TBX2 T-box 2 4.23775
KLHL21 kelch-like family member 21 3.69757
BMP4 bone morphogenetic protein 4 3.36026
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 3.32638
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.27542
ANO1 anoctamin 1, calcium activated chloride channel 2.60902
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.34305
WIF1 WNT inhibitory factor 1 2.21483
ZMIZ1 zinc finger, MIZ-type containing 1 2.20249
SNAP25 synaptosomal-associated protein, 25kDa 2.19089
CCL2 chemokine (C-C motif) ligand 2 2.07743
ABT1 activator of basal transcription 1 2.06069
MSRA methionine sulfoxide reductase A 2.0422

decreased expression

Symbol Name Standardized Value
GOLT1B golgi transport 1B -3.79092
HSPA8 heat shock 70kDa protein 8 -3.61253
HAT1 histone acetyltransferase 1 -3.5869
COG2 component of oligomeric golgi complex 2 -3.48189
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.3631
TXNDC9 thioredoxin domain containing 9 -3.28461
CD81 CD81 molecule -3.22874
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.86975
SGK1 serum/glucocorticoid regulated kinase 1 -2.79837
UBE3C ubiquitin protein ligase E3C -2.52563
PCCB propionyl CoA carboxylase, beta polypeptide -2.27526
HMG20B high mobility group 20B -2.24873
RGS2 regulator of G-protein signaling 2 -2.23426
HSPA1A heat shock 70kDa protein 1A -2.21458
S100A8 S100 calcium binding protein A8 -2.18691
HOXA5 homeobox A5 -2.18414
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.12628
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.04084